This fact sheet will explain all you need to know regarding the safe administration of Metronidazole including dosage, pharmacodynamics, side effects, interactions, contraindications and administration. Perfect for student midwives!
BASICS: DOSAGE:
• Antimicrobial medicine • Oral: 400mg every 8 hours (t.d.s.) or
500mg every 8 hours (t.d.s.) for 7 days
• Prevention of post-operative infections
• IV infusion: 500mg every 8 hours for 7
• Treatment of septicaemia, cellulitis, wound
days, given over 20 minutes
infections etc.
• Surgical prophylaxis: 400-500mg to be ad-
• Tablets or solution for injection or IV
ministered 2 hours before surgery, then
infusion
400-500mg every 8 hours if required for
• POM
24 hours.
• If topical cream used - avoid exposure to • Contraceptives - reduce effect
strong sunlight or UV light
• Hypersensitivity
PHARMACODYNAMICS: FETAL/BREASTFEEDING RISK:
• Antimicrobial agent acting on wide range • Avoid high dose regimes - 1st trimester
of anaerobic bacteria and protozoa use could lead to congenital
malformations e.g. limb defects
• Absorbed in the GI tract - peak plasma
concentration is 20 mins to 3 hours • Should only be given if essential as
insufficient evidence on safety in
• Excreted in the urine via the kidneys
pregnancy and lactation
• Excreted in breastmilk however amount
thought to be less than the therapeutic
dose for infant
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller ameliafletch2000. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £5.49. You're not tied to anything after your purchase.
