This fact sheet will explain all you need to know regarding the safe administration of Augmentin (Co-amoxiclav) including dosage, pharmacodynamics, side effects, interactions, contraindications and administration. Perfect for student midwives!
BASICS: DOSAGE:
• Antibiotic - broad spectrum penicillinase • 375mg or 625mg (if severe infection) t.d.s.
against amoxicillin resistant organisms tablets orally
• UTIs, prophylaxis • 600mg-1.2g if IV infusion
• POM
• Tablets, suspension, powder for
reconstitution
SIDE EFFECTS: PHARMACODYNAMICS:
• Nausea • Semi-synthetic penicillin that inhibits
• Diarrhoea enzymes that are involved in cell wall
synthesis
• Rashes
• Augmentin contains amoxicillin and
• Rarely - hepatic impairments
clavulanic acid that inactivates beta
CONTRAINDICATIONS: lactamase enzymes which stops the
amoxicillin being affected and therefore it
• Penicillin hypersensitivity
can kill the resistant bacteria
• Hepatic dysfunction :
• Eliminated via the kidneys
INTERACTIONS: FETAL/BREASTFEEDING RISK:
• Anticoagulants • Benefits must outweigh the risks if using
it - from manufacturer
• Methotrexate
• Not for use in 1st trimester
• Crosses into breastmilk - can cause
GUIDELINES:
diarrhoea and constipation as it can affect
• BNF - avoid in PPROM as possible the gut flora
increased risk of necrotising enterocolitis
in newborns
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller ameliafletch2000. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £5.49. You're not tied to anything after your purchase.
