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Assay-based coursework
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This piece of coursework was based on five papers given to us, we had to design the assays we thought had been described in the document and create original figures and figure legends for each assay. A second section discusses the interactions occurring in each assay and the pros/cons of the assays.

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  • February 6, 2022
  • 12
  • 2020/2021
  • Other
  • Unknown

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SCHOOL OF PHARMACY & BIOMOLECULAR SCIENCES


BIOCHEMISTRY PROGRAMME COURSEWORK COVERSHEET


LEVEL 6 COURSEWORK

MODULE CODE: 6101BCBMOL

MODULE TITLE: Advanced Structural and Functional Biochemistry

MODULE LEADER: Andrew Powell

COURSEWORK TITLE: Molecular interactions

TUTOR FOR WHOM THE WORK IS FOR: Andrew Powell


DATE SET AND WEEK NUMBER: 28.09.20 Week 1

DATE HANDIN AND WEEK NUMBER: 16.11.20 Week 8

DATE FEEDBACK AND WEEK NUMBER: 14.12.20 Week 12

% OF MODULE MARK: 40


HOW THE WORK IS TO BE HANDED IN

VIA CANVAS/TURNITIN YES
VIA STUDENT ZONE IN LIBRARY
DIRECT TO TUTOR
POSTER
ORAL
INCLASS ASSESSMENT


ANY SPECIAL INSTRUCTIONS: To facilitate anonymous marking write you student
number but not your name on the top right hand side of each page.

, 6101BCBMOL Student ID: 829886
WORKSHOPS ARE BEING HELD IN WEEKS 4-6. THE WORKSHOP IN WEEK 6 IS THE
LAST CHANCE FOR FEEDBACK PRIOR TO SUBMISSION, SO START EARLY .


COMPLETE SECTION A AND B (80 MARKS TOTAL).


Section A

Deconstructing written information in papers into a schematic diagram helps realise understanding of the
elements of a technique, helping the key features and pros/cons become apparent (e.g. for Section B).

Draw an ORIGINAL annotated schematic diagram as a figure, with figure legend, showing and
explaining the details of the main interaction technique used in the FIVE papers shown below. It is likely
that you will also need to access the Supplementary Information file from the website to access the
methods section.
10 marks per schematic


1. de Paz et al (2006). JACS: 128: 2766-7.https://pubs.acs.org/doi/pdf/10.1021/ja057584v

A




NH2




O
HN
N
O
O O O O




B NaO3SO
CO2H HO
HO
OH
NaO3SO O
NaO3SHN O OSO3H
O
O




O O
S S
O O

HN HN HN
NH NH

O O O O O O O O O O




4 9 10 11 12

1

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