Lecture notes
Haematopoiesis and introduction to blood cells
- Module
- Blood Science (6H5Z1003)
- Institution
- Manchester Metropolitan University (MMU)
Lecture notes on Haematopoiesis and introduction to blood cells
[Show more]
Content preview
Αἲμα – bloodλόγος-study
Haematology is the branch of science concerned with the study of
blood, blood-forming tissues and the disorders associated with them
Blood composition
Haematopoiesis
All cells of the blood originate from multipotent stem cells in the bone marrow - haematopoietic stem cells (HSCs)
1. Erythropoiesis: the formation of red blood cells
2. Myelopoiesis: the formation of white blood cells
3. Thrombopoiesis: the formation of platelets
Stem cells are undifferentiated cells that have two unique features:
1. Capacity of self-renewal
2. Ability to differentiate into a variety of mature cell types
, - HSCs are rare, ≈ 1 in every 20 million nucleated cells in the bone marrow
- Long-term HSCs: able to repopulate the bone marrow for › 16 weeks
- Short-term HSCs: engraft transiently for few weeks
- CD34+ CD38- LIN- = Appear like a medium size lymphocyte
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller polinalobacheva. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £9.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
75323 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy revision notes and other study material for 14 years now