Lecture notes
Bone infection pathology
- Module
- Medicine
- Institution
- Queens University Belfast (QUB)
Lecture notes of 15 pages for the course Medicine at QUB (Pathology)
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BONE INFECTION Acute ChronicOsteomyelitis haematogenous
contiguous
Infection in the bone can arise by two means
1st Spread of bacteria from other parts of bodythrough
the
the blood stream colonising and then infecting the bone
marrow
Haematogenous spread There are three main
sources of 10 infection staph la coccus aureus causing
soft tissue infection Ce g from Plc Neisseria gonnorn
oea
causing urethral infection t
Mycobacterium
tuberculosis causing lung infection
2nd Contiguous spread where bacteria spread directly
to the bone
usually from a more superficial skin lesion
Two common examples Trauma or chronic ulceration
of the skin
Typical osteomyelitis can occur in children
acute
when infection occurs at the epiphy seal growth plate in
haematogenous spread
Chronic osteomyelitis is more common in adults with
limb neuropathy 1 ischaemic e g In diabetics
, Presentation of OM Typically pain localised to the
infected bone fever pain when the infected bone
swelling at thearticu ates
infection
site of redness
tenderness It is generally quite easy to find the infection
site affected
when
long bones are It is more difficult
if the axial skeleton skull is involved
Chronic osteomyelitis is often seen in patients with
diabetes who have ulceration of the skin This can be
more difficult to
diagnose due to co existingneuropathy
Patients do not feel the
pain of the inflammatory process
Diabetes is also associated with chronic ulceration so
pts may not notice a particular change
Chronic Acute 0M caused
by IO
OM access in Resus
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