Normal cardiac
LVDtHF
function
The circulation Phases of the cardiac
cycle
A Diastole C relaxation filling
is ovolumic
filling
Early filling
Diastisis
Late filling Active
B Systole contraction
I so volumic contraction
Ventricular ejection
cardiac output
The volume of blood pumped around the
body in one min
Co Stroke volume X HR
Vol is determined
Stroke by cardiac stretch and
inotropic status among other factors
Calculation of Left ventricular ejection fraction
LV EF End diastolic VIX End
systolic Vol
C nd diastolic Vol X 100
, Cardiac output is also affected by the conditions into
which the heart pumps
Resistance to pumping C vascular resistance
Arterial blood pressure
CO Arterial pressure vascular resistance
Starling's law Preload
Increased volume at
the end of diastole
means the heart will
eject a greater stroke
Volume The volume of
the heart at the end of
diastole is
directly related
to the filling pressure of
the heart Cp reload
Pathophysiology of Heart failure
A clinical syndrome in which a cardiac abnormality
impairs its pump function and ability to support a
physiological circulation
Ejection fraction Systolic volume
noo
C nd diastolic volume
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