Lecture notes
Management of anaemia
- Module
- Medicine
- Institution
- Queens University Belfast (QUB)
Haematology pathology
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ANAEMIA MANAGEMENTPractical aspects of transfusion Sourcing safe blood
screening tests group1 cross match safe infusions
ABO system Rh
system C c D Ee
Anti D antibodies present
A Rh D p t transfused with
Rh Dt blood
B Rh D worn and pregnant with Rh Dt baby
Selecting blood for transfusion
A B Universal recipient
C no antibodies
0 Universal donor
no antigens
, for blood t blood
Key requirements establishments
banks by Blood Safety and Quality Regulations
are set
BSQ R t Medicines and health care productsregulatory
agency MHRA Establishments must be licensed
MHRA can remove this
All donors must criteria outlined in UK Donor
satify
Selection guidelines issued
by J P AC
Testing t screening blood
A Blood
groups t antibodies Every donation screened
to determine AB Ot Rh Status as well as plasma screening
for antibodies
B Screening for infectious agents Mandatory HepB
HIV syphilis Hep C Human T cell lymphotropic virus
Where indicated Malaria West Nile Trypanosoma
cruzi
Compatibility procedures
A Group t screen Pt pre transfusion blood sample
to determine AB Ot Rh D status Plasma is screened for
all 0 antibodies
capable of causing transfusion reaction
normally done using automated analysers to reduce
human error and safer than manual technique Compatible
blood group then selected
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