This presentation is mainly focused on the G-protein coupled receptors, such as their classification, mechanism, and physiological role in the human body.
01 02
G-Protein GPCR in drug
coupled receptor discovery
Nguyen Thi Ngoc Anh Lương Thị Hoa
Nguyễn Thành Trung Nguyễn Minh Sơn
,01
G-Protein
coupled
receptor
, 1. G-Protein coupled receptor
Historical GPCR GPCR
background Overview Classification
Brief history of the discoveries Definitions of GPCRs, their The classification of GPCRs is
of GPCRs and the research distinctive features and based on the differences in
achievements of scientists their application to the their structure, function
drug's target. and subject
Mechanism Physiological
of GPCR role
The communication mechanisms of GPRCs and Ability to amplify the message contributes to their
G proteins lead to the activation of two significant role in many physiological pathways,
intracellular communication pathways. dysregulation of which contribute to many diseases
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