Exam (elaborations)
Cell Biology 2018 Exam Paper
- Module
- Cell Biology
- Institution
- Imperial College London (ICL)
Cell Biology 2018 Exam Paper
[Show more]
Content preview
IMPERIAL COLLEGE LONDONB.Sc. Examination 2018
This paper is also taken for the relevant examination for the Associateship of the Royal
College of Science
INTEGRATIVE CELL BIOLOGY
Monday 18 June 2018 10.00 - 13.00
FOR SECOND YEAR STUDENTS IN BIOCHEMISTRY AND BIOTECHNOLOGY
Answer any THREE questions. Answer each question in a separate book. Parts of a
question carry equal weighting unless otherwise specified.
1. Addition of epidermal growth factor (EGF) to cells expressing the EGF receptor
leads to transcription of the early response gene c-fos. Describe the full
sequence of events that link growth factor binding to target gene transcription.
2. You are studying a hormone that acts through a G protein-coupled receptor
(GPCR). Adding the hormone to cells expressing its receptor results in
oscillations of intracellular [Ca2+]. Propose a mechanism that explains this
behaviour and discuss how the [Ca2+] oscillations may ultimately lead to
phosphorylation of effector proteins.
3. How strong is the evidence that Alzheimer’s and Parkinson’s disease are caused
by prion-like mechanisms?
4. Discuss fast and slow neurotransmission and the different roles they have in the
nervous system.
5. Why do we need different functional classes of CD4 T cells? Describe their roles
in adaptive immune responses.
6. Define what a stem cell is (15%). Discuss how stem cells can be used to learn
more about disease mechanisms and how they might be used as disease
treatments (85%).
End of paper
© Imperial College London
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller christyau. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £4.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
70055 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy revision notes and other study material for 14 years now