This document contains all the relevant student knowledge pertaining to bipolar disorder. This includes:
Type 1 vs type 2
Aetiology
Symptoms
Formal diagnosis
Medical management
A mood disorder characterised
by depression mania and
hyp mania
Age incidence peaks are 15 24 and 45 54
Aetiology
A Genetics There is an t risk of developing Bi
polar if a first
degree relative is diagnosed The genetic risk is known as
polygenic inheritance which is the sum effect of many
low penetrance mutations
B Environmental Negative life events and circadian
rhythm disruption in geneticallypre disposed individuals
c Neurobiological There is some evidence of t dopamine
activity in the brain be an important aetiology in
may
mania
Clinical features
A Bipolar 1 At least one episode of mania
B Bipolar 2 No mania at least I hypomania depression
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