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Summary Notes for kidneys and osmoregulation

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11.3.1 Animals are either osmoregulators or osmoconformers. 11.3.2 The Malpighian tubule system in insects and the kidney carry out osmoregulation and removal of nitrogenous wastes. 11.3.3 The composition of blood in the renal artery is different from that in the renal vein. 11.3.4 The ultrastru...

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  • March 12, 2023
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IB Biology HL: 11.3 The Kidney and Osmoregulation Notes

Excretion: the removal from the body of the waste products of metabolic activities (urine, sweat,
expired air)

Egestion: the process of discharging undigested or waste material from a cell or organism
(feces)




The nephron is the functional unit of the kidney and includes:
 Afferent arteriole: Brings blood to the nephron to be filtered
 Efferent arteriole: Removes blood from nephron (minus filtered components)
 Glomerulus: Capillary tuft where filtration occurs
 Bowman's Capsule: First part of nephron where filtrate is collected
 Proximal Convoluted Tubule: Where selective reabsorption occurs
 Loop of Henle: Important for establishing a salt gradient in the medulla
 Distal Convoluted Tubule: Final site of selective reabsorption
 Collecting Duct: Feeds into ureter and is where osmoregulation occurs
 Vasa Recta: Blood network that reabsorbs components from the filtrate

Osmolarity: refers to solute concentration of a solution

Osmoregulators: maintain a constant internal solute concentration regardless of the osmolarity
of their environments
 all terrestrial animals, freshwater animals and some marine organisms (bony fish) are
osmoregulators
 these marine organisms maintain solute concentration at about one-third of the
concentration of seawater and about 10 times that of fresh water

, Osmoconformers: animals whose internal solute concentration is the same as the concentration
of solutes in the environment

Malpighian tubule system:

 Hemolymph: fluid with characteristics of tissue fluid and blood; circulated throughout
bodies of many invertebrates
 Uric acid: nitrogenous waste product of protein metabolism; toxic and must be excreted
 Malpighian tubules: branch off from intestinal tract
 Cells lining the tubules actively transport ions and uric acid from hemolymph into the
lumen of the tubules
 This draws water by osmosis from the hemolymph through the walls of the tubules into
the lumen
 Tubules empty contents into the gut
 In the hindgut, most of the water and salts are reabsorbed while the nitrogenous waste is
excreted with feces

Compostion of blood renal artery vs renal vein:
 Kidneys are responsible for osmoregulation and excretion – remove substances from
blood that are not needed or are harmful
 Renal artery brings blood into kidney and renal vein brings blood out of kidney
 Substances in higher concentrations in the renal artery (compared to renal vein) include:
o Toxins that are ingested and absorbed but not fully metabolized (ex. betain
pigments in beets, drugs)
o Excretory waste products including nitrogenous waste products (ex. urea)
o Excess water and salt (not excretory waste products, part of osmoregulation) –
concentrations of water and salt are more variable in the renal arteries and more
constant in the renal veins
 Kidneys filter off about one-fifth of the volume of plasma from the blood flowing
through them
 Filtrate contains all of the substances in the plasma except large protein molecules
 Kidneys then actively reabsorb specific substances the body needs and unwanted
substances are eliminated in the urine
 Unwanted substances are present in the renal artery but not the vein
 Blood leaving the kidney through the renal vein is deoxygenated and has a higher partial
pressure of CO2 compared to the renal artery due to the metabolic activity of the kidney
 Some glucose is used for cellular respiration by the kidney, making the concentration in
the renal vein slightly lower than in the renal artery

Glomerulus and Bowman’s capsule:
 Ultrafiltration occurs when hydrostatic pressure forces plasma through a semi-permeable
membrane, separating blood cells and large proteins from the remainder of the serum
 Ultrafiltration occurs between the glomerulus and the Bowman's capsule and requires two
things to form the filtrate:

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