100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Previously searched by you
Previously searched by you
logo
Protein Biochemistry and enzymology £5.49
Add to cart
Quickly navigate to
Preview
  2.  
  3. Cardiff University (CF)
  4.  
  5. BI1014 - Biological Chemistry (BI1014)

Lecture notes

Protein Biochemistry and enzymology
 26 views  1 purchase

Lecture notes from the BI1014 module Protein biochemistry and enzymology. Lecture notes written in 2023, some content missing due to strike action, however that will not be assessed this year.

Preview 2 out of 6  pages

Document information

  • April 18, 2023
  • 6
  • 2022/2023
  • Lecture notes
  • Professor colin berry
  • All classes

Subjects

Written for

All documents for this subject (1)

Seller

avatar-seller
lillytait

Content preview

Enzymes

 Catalysts: Make reactions happen rapidly.
 Work under mild conditions.
 Specific for both reaction and substrate.
 Can be regulated.



 Substrate binds to enzyme (Rapidly reversible process).
 Reaction occurs and product(s) dissociate.

Low [S]: As [S] increases: High [S]:
At any instant only a small fraction of enzyme Most enzyme molecules
fraction of the enzyme molecules bound to have substrate bound.
molecules are substrate substrate increases. {SATURATION}
bound.

Michaelis-Menten equation

, Protein structure

Stabilisation of 3 ̊ Structure
 Van der Waals
 H-bonds

Disulphide Bonds
Covalent bonds
between two cysteine side-chains

-CH2-SH HS-CH2-
-CH2-S-S-CH2-

Ion pair bond (Salt Bridge) Ionisation




Domains
 Domain: globular unit formed from part of polypeptide.
o Domains often associated with a particular function EG yeast hexokinase.
o Large domain binds ATP Glucose binds between.

Quaternary Structure
Assembly of more than one polypeptide chain

Folding – Function
 Structure/Activity
 Necessary for drug design
 Necessary for protein engineering

Primary – Sequence of amino acids.
Secondary – Helices and sheets.
Tertiary – 3D structure – folded polypeptide.
Quaternary structure – Assembly of >1 folded polypeptide.

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller lillytait. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for £5.49. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

56326 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy revision notes and other study material for 14 years now

Start selling
£5.49  1x  sold
  • (0)
Add to cart
Added