Type of Concept Health and Illness: Oxygenation
Concept Perfusion
Concept Definition The flow of blood through arteries and capillaries to deliver nutrients and
oxygen to cells and remove cellular waste products.
Scope or Categories Ranges from optimal perfusion to no perfusion
of Concept Central perfusion (mechanisms for blood delivery) and local or tissue
perfusion (actual amount of blood available to target tissues)
Definitions Ischemia
It refers to lack of blood flow to a part of the body. Ischemia can result to
damage of tissues as a result of lack of nutrients and oxygen. It occurs due to
partial of full blockage of the hear arteries.
Infarction
It takes place when blood supply to a part of the cardiac muscle is fully
blocked. This leads to a lengthy tissue ischemia and permanent cell damage.
Anoxia
It is occurs when there is limited supply of oxygen to a body part tissues
despite sufficient blood supply to the tissue.
Populations at Risk/ Populations: all individuals, regardless of age, gender, race, or socioeconomic
Individual Risk status, are potentially at risk for impaired perfusion. Some risk factors are
Factors controllable lifestyle behaviors, some are not. Populations at greatest risk are
middle age and older adults, especially males and African Americans. Also at
risk are infants with congenital heart defects.
Individual: Modifiable risk factors: smoking, elevated serum lipids, sedentary
lifestyle, obesity, diabetes mellitus, and hypertension; unmodifiable risk
factors: age, gender, and genetics
Risk Factors Age – middle and older age groups
pathophysiology and o Rationale: Atherosclerosis, myocardial disease, and other
modifiability chronic diseases affecting cardiovascular function are more
prevalent in these age groups. Older adults also have more
fibrosis and sclerosis of the sinoatrial node and of the
mitral and aortic valves.
o Modifiable?: No.The possibility of men getting CAD
escalates between 45-50 years while that of women
escalates between 55-60 years.
Sex – male
o Rationale: Atherosclerosis, myocardial disease, and other chronic
diseases affecting cardiovascular function are more prevalent in
men.
o Modifiable?: No. The connection between sex and CAD threat is
differentiated by age. Middle aged women have lower possibilities
f developing CAD while after menopause the possibility of getting
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