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Unit 10.B Respiration in Humans
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Unit 10: Biology Molecules and Metabolic PathwaysRespiration In Humans
Introduction:
Respiration and breathing are two distinct processes. Moving air into and out of the lungs (inhalation
and exhalation) is the act of breathing. All living things produce energy, or ATP, during the process of
breathing. Adenosine triphosphate, also known as ATP, is a phosphorylated nucleotide with a structure
resembling that of DNA and RNA. The cell in which ATP was created prevents it from leaving. All animal
cells contain mitochondria, where it takes place. Two membranes are present in the mitochondria,
which is significant because it enables the separation of the aerobic respiration reactions from the rest
of the cell. Enzymes are also crucial for the Krebs Cycle and Link Reaction phases of respiration. These
enzymes are kept in the mitochondria's matrix. The cristae of the mitochondria provide a sizable surface
area, which is crucial because it enables numerous Electron Transport Chains.
Why is respiration important? Cells must respire in order to produce energy, which enables other bodily
functions to run smoothly. Active transport, muscle contraction, the synthesis of proteins and enzymes
from larger molecules, the production of cellulose from glucose, starch from glucose, and amino acids
from glucose and nitrates are a few bodily processes that depend on the energy generated during
respiration.
Aerobic Respiration – Utilising oxygen is aerobic respiration. This happens in plant and animal cells as
well as a small number of microbes. Compared to anaerobic respiration, aerobic respiration is more
effective and produces more energy. In the region of 32 ATP molecules, energy is released from the
glucose and oxygen. In mitochondria, aerobic respiration takes place.
Equation: Glucose + Oxygen Carbon Dioxide + Water
Anaerobic Respiration – Respiration that takes place in animal, plants, and some microbial cells in
condition of low oxygen or absence of oxygen. Some examples of where anaerobic respiration occur
include plant roots in waterlogged soil, bacteria in puncture wounds and human cells during vigorous
exercise. Anaerobic respiration in microbes can be used to make useful products. Bacteria are used to
break down waste to make biogas. Yeast is used to make carbon dioxide in dough to make bread rise.
Yeast can also be used to ferment sugars to make alcohol in beer and winemaking. Less energy is
released (2 ATP molecules) than that of aerobic respiration.
Equation: Glucose Lactic Acid (some energy released).
Or
Glucose Ethanol + Carbon Dioxide (some energy released)
, The body uses anaerobic respiration to produce energy in an effort to compensate for the oxygen
deficiency that occurs when the heart cannot pump enough blood to the muscles during exercise while
using aerobic respiration. The amount of energy released from glucose is less. When there is insufficient
oxygen for aerobic respiration, it occurs. Anaerobic respiration is a temporary solution because too
much lactic acid produced after anaerobic respiration can cause mouth sores or a metallic taste. You get
tired after engaging in a lot of physical activity because lactate builds up in the cells and causes fatigue.
It is a waste item. When oxygen is not readily available for aerobic respiration during exercise, our cells
produce lactate to provide energy. Because lactate enables the breakdown of glucose, it is possible to
produce ATP without the use of oxygen. Pyruvate is momentarily changed into lactate, enabling the
breakdown of glucose.
An oxygen debt is created during anaerobic respiration. This is how much oxygen is required to convert
lactic acid to carbon dioxide and water during the oxidation process. This is due to the fact that glucose
does not completely decompose into carbon dioxide and water. Lactic acid is created when some of it is
broken down. The liver breaks down the lactic acid, turning some of it back into pyruvate, which then
goes through aerobic respiration, which needs oxygen. We continue to breathe deeply and quickly for
some time after exercise, which can be attributed to the presence of an oxygen debt.
Stages of Respiration – P2
Glycolysis:
The first phase of respiration, known as glycolysis, takes place during both aerobic and anaerobic
respiration. This stage's goal is to break down large glucose molecules into smaller ones known as
pyruvate. The mitochondria, a double-membrane organelle found in human cells, can then receive this.
It is crucial to begin the glycolysis stage with 2 ATP because doing so will enable the production of more
ATP later on. Due to its rapid division into two molecules of trise phosphate, phosphorylated glucose is
incredibly unstable. Triose phosphate, also referred to as pyruvate, is oxidised to produce pyruvic acid.
This is accomplished by the coenzyme NAD, and as a result, NADH (reduced NAD) is produced. A redox
reaction is what is happening here, where one molecule is reduced and the other is oxidised. The end
products of glycolysis are 2 ATP, 2 x NADH, and 2 x pyruvate. There are now four ATP in total. The
substrate-level phosphorylation of this ATP is an illustration.
Glycolysis is an energy-intensive process. The other stages of respiration would not be possible without
glycolysis. The respiration process is essentially "kick-started" by the energy that glycolysis needs to take
place. By the end of this phase, more ATP can be produced because it only uses a small amount of ATP.
In contrast to glycolysis, which needs energy to proceed, the following stages finish converting pyruvate
into ATP and NADH. The energy generated here is for use by the cell.
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