GCSE
BIOLOGY
Foundation Tier Paper 2F JUNE 2022
Time allowed: 1 hour 45 minutes
Materials
For this paper you must have:
• a ruler
• a scientific calculator.
Instructions
• Use black ink or black ball-point pen.
• Pencil should only be used for drawing.
• Fill in the box...
Candidate signature
I declare this is my own work.
F
GCSE
BIOLOGY
Foundation Tier Paper 2F JUNE 2022
Time allowed: 1 hour 45 minutes
Materials
For Examiner’s Use
For this paper you must have:
a ruler Questio Mark
a scientific calculator. n
1
Instructions 2
Use black ink or black ball-point pen.
3
Pencil should only be used for drawing.
4
Fill in the boxes at the top of this page.
Answer all questions in the spaces provided. 5
If you need extra space for your answer(s), use the lined pages at 6
the end of this book. Write the question number against your
7
answer(s).
Do all rough work in this book. Cross through any work you do 8
not want to be marked. 9
In all calculations, show clearly how you work out your answer. 10
Information TOTAL
The maximum mark for this paper is 100.
The marks for questions are shown in brackets.
You are expected to use a calculator where appropriate.
You are reminded of the need for good English and clear
presentation in your answers.
*JUN224612F01*
IB/M/Jun22/E16 8461/2F
, 2
Do not write
outside the
Answer all questions in the spaces box
provided.
Maple
0 1syrup urine disease (MSUD) is a rare inherited human condition. The
allele for MSUD is recessive.
0 1 .1 What is a recessive
allele? [1 mark]
Tick () one box.
An allele expressed only if a person has two copies of the
allele
An allele expressed only if it is inherited from the male parent
An allele expressed when it is found on only one of the
chromosomes
Figure 1 shows the inheritance of MSUD in one
family.
Figure 1
0 1 .2 The symbol is not in the key for Figure 1.
What would this symbol represent?
[1 mark]
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, 3
Do not write
outside the
Persons 1 and 2 in Figure 1 have a child with MSUD and some box
children without MSUD.
0 1 .3 Complete Figure 2 to show the possible genotypes of the
children.
Use the following symbols:
N = allele for not having MSUD
n = allele for MSUD [2 marks]
Figure 2
Person 2
N n
N Nn
Person 1
n
. What is the phenotype of a person with the
0 1 4
genotype Nn?
[1 mark]
0 1 .5 What percentage of the offspring in Figure 2 will have
MSUD? [1 mark]
Tick () one box.
25% 50 75 100
% % %
Question 1 continues on the next page
*03
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, 4
Do not write
outside the
Turn over ►
*03
IB/M/
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