This is a practice paper (MCQ) for the main exam from the year 2022. It contains questions for every lesson and provides effective revision. It contains 2 sections with 45 questions in total.
4BBY1060 Practice main exam paper 2022 - Without
Answers
Fundamentals of physiology and anatomy (King's College London)
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4BBY1060 ‘practice’ exam 2022 WITHOUT ANSWERS
Section 1. Physiology/anatomy and data interpretation. 25 single best answer MCQs. For
each question, choose the SINGLE best answer from the five options given (A, B, C, D or E).
Each correct answer is worth 1 mark, while incorrect answers or answers left blank earn 0 marks.
Total 25 marks. Recommended time 40 minutes.
1) Which statement best describes the polarity of epithelial cells?
a) It indicates the direction of flow of ions across the cell membrane: inward at the
apical surface and outward at the basolateral surface
b) It tells you which is the ‘upper’ and which is the ‘lower’ surface of the cell
c) It highlights the fact that the apical surface is positively charged while the
basolateral surface is negatively charged
d) There are structural and functional differences between the ‘apical’ and
‘basolateral’ surfaces of the cell
e) It is the way in which cells align themselves at 90 degrees to the flow of material
through tubes (blood vessels, airways, renal tubules, GI tract etc)
2) Which statement best describes the structure and function of striated
muscle?
a) It has regular bands composed of an M line, a Z disc and interdigitated actin and
myosin fibers. Contraction required binding of Ca 2+ to tropomyosin
b) It has a smooth appearance, being composed of loosely organised interdigitated
actin and myosin fibers. Contraction required binding of Ca 2+ to troponin
c) It has regular bands composed of an M line, a Z disc and interdigitated actin and
myosin fibers. Contraction required binding of ATP to troponin
d) It has regular bands composed of an M line, a Z disc and interdigitated actin and
myosin fibers. Contraction required binding of Ca 2+/calmodulin to myosin light-
chain kinase
e) It has the appearance of highly regular bands composed of an M line, a Z disc and
interdigitated actin and myosin fibers. Contraction required binding of Ca 2+ to
troponin
Continued on next page
3) Below is a drawing of the heart. Which of the structures (a, b, c and d) are
involved in the delivery of oxygenated blood to the systemic circulation?
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a) ‘a’
b) ‘b’ only
c) ‘c’
d) ‘b’ and ‘d’
e) ‘d’ only
4) Which statement best describes skin blood flow?
a) At rest, it is kept low through myogenic autoregulation but during exercise this is
over-ridden by accumulating CO2, resulting in vasodilation
b) In response to an increase in core temperature, anastomoses below the
epidermis constrict
c) In response to an increase in core temperature, anastomoses below the
epidermis dilate
d) It is only controlled by highly localised changes in temperature and is not
influenced by the autonomic nervous system
e) It is increased during sustained exercise so to direct blood toward the working
skeletal muscles
Continued on next page
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