This is my own coursework for the Physiology summative coursework, which experimentally sees the effect of moving from a supine to a standing position on the mean arterial blood pressure.
Aim:
To determine experimentally whether moving from a supine to a standing position influences mean
arterial blood pressure (MAP). 18 Words
Methods:
A total of 40 subjects’ blood pressure (BP) was measured when in supine and standing positions, from a
population of healthy students of both female and male genders. An automatic sphygmomanometer was
used to measure their systolic and diastolic blood pressure, by placing the cuff on the brachial artery of
the upper arm. Their blood pressure was taken 3 times for when sitting down on a chair (supine) and
when in standing positions, with 3-minute intervals between each measurement, to allow for recovery.
This allows us to come up with averages and avoid anomalies in blood pressure as a result of
environmental influences. Their average diastolic and systolic blood pressure measurement was used
to calculate Mean Arterial Pressure (MAP) for supine and standing positions, using the equation ((MAP
= DBP + ((SBP - DBP)/3)). A paired, two-tailed t-test was used to see if there is a significant difference
in MAP when moving from supine to standing position. 157 words
Results:
Blood Pressure (mmHg)
Systolic Blood Pressure Diastolic Blood Pressure Mean Arterial Pressure
(SBP) (DBP) (MAP)
Position MEAN SEM P value MEAN SEM P value MEAN SEM P value
*N=40
*MAP differences are significant at 0.05 level. P values obtained using a Paired, 2 sided T-test at 0.05
significance level
*P values obtained using a Paired, 2-sided T-test.
*SEM= Standard Error of the Mean
*mmHg= millimetres of mercury (unit of measurement for blood pressure)
Fig.1: P values obtained from MAP values when in Supine and Standing positions
Overall, the table shows that in the 40 subjects, when moving from supine to standing position, SBP,
DBP and MAP increase, as the mean values for all 3 measurements of BP in supine position is lower than
in standing position. SEM values for the 3 measurements of BP in supine position is lower than standing,
suggesting that the means of standing are more widely spread around population mean (e.g. 121.53
mmHg for Mean of SBP). All P values<0.05, thus difference in MAP from supine to standing is significant.
87 words
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