If you're studying a life science (e.g. - biomed, bioscience, physiology, sports science, sports physiology etc), then this detailed set of lecture notes on cilia and mitochondria will help you smash your first set of exams on cell/molecular biology!
You'll need a good knowledge of this you'll ...
Structure depends on required function – e.g. – centrioles need lots of strength so 3, but flagella need
to move – less strength needed
Grow out from centrosome – (near nucleus) – anchored in place with triplet
Have a role in cell division
- Partition of replicated chromosomes
- Assembles and disassembles microtubule structure – forms mitotic spindle
- Centromere changes shape/structure – pulls chromatids
- 9 triples (27) microtubules – surrounded by protein matrix
- 9+0 = no tubules in centre
- Centriole pairs form mitotic spindle – so equal division of genetic material
Mitotic spindle controls chromosome movement
- 2x centrosomes (replication) – opposite poles of cell
- Microtubules grow out of them
Centrosome at prometaphase = Aster
- Tubules = down to midline and attached to kinetochore – attaches to chromatin
- Microtubules shorten (anaphase) – depolymerise at kinetochore ends – sister chromatids
more to opposite ends of cell
- Breaks down of microtubules = pulling motion
- Kinetochore breaks down microtubules – releases tubulin subunits
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