ASCP MLS Exam Questions & Answers 2023/2024
What feature is most often found with patients with a splenectomy on a Wright's stained blood smear? - ANSWER-Howell-Jolly bodies
Patients with antibody to the following antigen are immune to Hepatitis B: - ANSWER-Surface antigen (HbSAg)
Which ...
What feature is most often found with patients with a splenectomy on a Wright's stained blood smear? -
ANSWER-Howell-Jolly bodies
Patients with antibody to the following antigen are immune to Hepatitis B: - ANSWER-Surface antigen
(HbSAg)
Which two of the following tests are helpful for documenting previous Streptococcal throat and skin
infections: - ANSWER-ASO titer and Anti-DNase B
In mass spectrometry, the "appearance potential" is defined as the: - ANSWER-Minimum energy
required for the appearance of a particular fragment ion in mass spectrum
What is generally accepted as the lower threshold value for semen pH from fertile males? - ANSWER-7.2
Coulometry: - ANSWER-An automated method for measuring chloride which generates silver ions in the
reaction
Erythroleukemia: - ANSWER-Also known as Acute Myelogenous Leukemia type M6. This type is
associated with either the presence of both erythroid and myeloid precursors OR strictly erythroid
precursors.
Myelomonocytic leukemia - ANSWER-Is associated with an increase in myeloid and monocytic cell
precursors, but not red blood cell precursors
Species that are Lysine (+), arginine (=) and ornithine (+): - ANSWER-Enterobacter aerogenes,
Edwardsiella species and most Serratia species
,Lysine reaction for all Citrobacter: - ANSWER-Negative
Key identifying characteristic for Pantoa (Enterobacter) agglomerans: - ANSWER-negative reactions for
the three decarboxylases commonly tested ( Lysine, arginine and ornithine)
Which organism is MOST likely responsible for septic reactions associated with Red Blood Cell
transfusions? - ANSWER-Yersina entercolitica is most likely responsible for septic reactions in
transfusions of Red Blood Cells. This organism is usually acquired by ingestion of contaminated food and
causes mild symptoms of abdominal pain and diarrhea. Growth of Y. entercolitica is enhanced in iron-
rich environments such as red cell components.
Gaucher's disease - ANSWER-The most common lysosomal storage disease caused by insufficient activity
of the lysosomal enzyme glucocerebrosidase that leads to the deposition of glucocerebroside in cells of
the macrophage-monocyte system.
Diseases associated with dysfunctions of polymorphonuclear neutrophils (PMNs) - ANSWER-Chediak-
Higashi syndrome (CH), Chronic granulomatous disease (CGD), Myeloperoxidase deficiency (MPO)
Nephrotic Syndrome: - ANSWER-Caused by damage to the kidneys, especially the basement membrane
of the glomerulus; which causes abnormal excretion of protein and red blood cells in the urine. Fats are
also present in the urine in most cases. A foamy appearance of the urine is a key characteristic of this
condition.
Clinical symptoms include:
Swelling
Weight gain from fluid retention
Poor appetite
High blood pressure
Key Biochemical reactions for Enterobacteriaceae: - ANSWER-The key biochemical reactions by which
the family Enterobacteriaceae can be identified include fermentation of carbohydrates, reduction of
nitrates to nitrites and the absence of cytochrome oxidase activity.
, ANA - ANSWER-See 2 quiz #27
Prozone effect: - ANSWER-Results in a false positive reaction; is the result of antibody excess and dilution
of antibody can help prevent its occurrence
Purpose of a bi-chromatic analyzer with dual wavelengths is: - ANSWER-Minimize the effect of
interference
Key characteristics of Micrococcus: - ANSWER-Susceptible to bacitracin ("A") and resistant to
furazolidone; gram positive cocci in tetras, bacteria cells of micrococcus luteus are larger than those of
the staphylococci and can arrange in tetras
What is the glomerular filtration rate for a patient with a serum creatinine of 2 mg/dL, if the urine
creatinine was 124 mg/dL and the urine volume was 2.2 L/24 hrs? - ANSWER-95 mL/min
One method of calculating a glomerular filtration rate is using creatinine and urine volume to determine
creatinine clearance. The equation is as follows:
Creatinine Clearance = (urine creatinine X urine flow rate) / plasma creatinine; where urine flow rate =
volume in mL /24 hours x h/60 min)
In this case = creatinine clearance = 124 X (2200/24 x hour/60) / 2 = 94.7 or 95 ml/min
Estrogen and progesterone markers are most commonly used to provide prognostic information about: -
ANSWER-Breast cancer
The prozone effect ( when performing a screening titer) is most likely to result in: - ANSWER-Prozone
effect (due to antibody excess) will result in an initial false negative in spite of the large amount of
antibody in the serum, followed by a positive result as the specimen is diluted.
Which of the following Rh antigens is found the highest frequency in the Caucasian population:
A. C
B. E
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