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Lecture notes

Drugs and Behaviour 4: CNS Depressants

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  • July 4, 2017
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Drugs and Behaviour - Andy Parrott

Lecture 4: CNS Depressants – 11th October 2016

CNS Depressants: Overview

 Alcohol as the archetypal CNS depressant
 Consumption patterns
 GABA receptor and neurochemical aspects
 Behavioural effects
 Drug tolerance, dependency, & alcoholism
 Barbiturates: Lethal with alcohol & now withdrawn
 Benzodiazepines: First developed in the 1960s and still widely used
 Many other CNS depressants: not covered today

GABA MIGHT BE AN EXAM QUESTION!

Archetypal  A typical instance of that class of items, alcohol is the classic drug
for the group of CNS depressants.

The main effect it has is on GABA. There are lots of drugs in this class but all have
slightly different effects. Alcohol is extremely damaging but as a drug it is one of
the safest. It is only very dangerous because it is widely used leading to large
numbers of alcohol related problems through society.

Alcohol consumption patterns

 Consumed for +10,000 years. Used in most societies.
 Babylonian laws to regulate drinking

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