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Lecture 2: Food Hypersensitivity and Food Intolerance
Hyperactivity and psychotic symptoms
Feingold
Benjamin F Feingold
Some develop intolerance to aspirin (acetylsalicylic acid)
Those sensitive to aspirin react to foods containing natural salicylates, similar
substances.
Aspirin sensitive patients react to the yellow colouring tartrazine (E102)
Those sensitive to tartrazine react to aspirin
o A yellow synthetic azo dye
o Typical products include fizzy drinks, fruit squash, puddings, cakes, sauces,
soups, sweets, jelly, ice cream, jams, honey products etc.
Aspirin and tartrazine produce either hives or a rash in those who respond to those
compounds.
While ill he became aware of a marked increase in hyperactivity among children
Estimated half to 5 million children affected of which half taking Ritalin (used to treat
ADHD and ADD).
25 years before when he was a paediatrician, hyperactivity was rare among children.
Noted that if the use of additives and the increase in hyperactivity was plotted, the
lines were parallel.
The Feingold diet was then developed on the premise that salicylates may trigger
hyperactivity.
In 1965, a woman in her early forties came with a swollen face and giant hives.
Placed on a diet avoiding artificial colours and flavours
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