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OCR A-Level Biology Synapses Summary

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Handwritten Summary by an Oxford Medical Student which covers all content necessary for an A* in Synapses at OCR Biology A-Level.

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  • October 11, 2023
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  • 2023/2024
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Excitatory Neurotransmitters Triggers an :
action
potential
-
Depolarisation

Inhibitory Neurotransmitters Prevents action :


potential s
Hyper polarisation
Presynaptic
Transmission of imprises
11 neurone



"Action potential reaches
many RER
end of


·Y
the presynaptic
-

lots of G the neurone




e
-C



minor
synaptic
I knob



Depolarisation of
Synaptic 2
the
presynaptic membrane
opens calcium
.




I synaptieft
ion channe a
reptationsmitte
.
3
Calcium ions diffuse into
presynaptic knob

4.
Synaptic resides
containing neurotransmitters fuse with the presynaptic membrane

S Neurotransmitter
.
diffuses across the
synaptic cleft by exocytosis
6 It binds with it's specific receptor molecule
post synaptic
.


on the membrane

-Sodium ion channels open and Nat diffuses into the postsynaptic neurone

↳Action potential is triggered
3




Cholinergic synapses Use the neurotransmitter accty, choline :




>Found in the CNS and neuromuscular
junction
Is
hydrolysed by acetylcholinesterase to produce Chlorine and ethanoic acid

Role of Synapses :




Ensure impulses are unidirectional

·Allow
divergence -> transmission into several neurones

-Allow stransmission into
convergence one neurone


Spatial Summation :
Several
Presynaptic neurones Connect to one postsynaptic neurone .




Temporal Summation One :



single presynaptic neurone releases several neurotransmitters

by several action
potentials triggered in a short period of time

Drugs Mimick the shape of the neurotransmitters
Stimulating more neurotransmitters
:
-




Blocking receptors

Central Nervous System
:
Brain and Spinal Lord

Peripheral Nervous System All that connect the CNS to the rest of the
the neurones
body
:




somatic Nervous System Nervous under conscious control
system Acetyl
:

->
choline

Autonomic Nervous under subconscious
System Nervous
system working constantly control
:




↳ Noradrenaline
↳ Sympathetic Nervous system Causes increased
activity
:




Parasympathetic Nervous Causes decreased
system activity
:

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