Exam (elaborations)
ONCC BMTCN EXAM SET 1 WITH COMPLETE SOLUTIONS 2023.
- Institution
- Oxford University (OX)
ONCC BMTCN EXAM SET 1 WITH COMPLETE SOLUTIONS 2023.
[Show more]
Content preview
BMTCN - CHAPTER 6 WITH COMPLETESOLUTIONS ALREADY GRADED A+
What are the types of cardiac diseases common post HSCT? What conditioning medications can
cause these diseases? - answer Cardiomyopathy, arrhythmias, congestive heart failure - high
dose cytoxan and radiation causes this
HTN/Dislipidemia: Immunosuppression meds
HTN/Hyperkalemia: Cyclosporine
HTN/Hyperlididemia and edema: Sirolimus
How would you management cardiac disease in post-HSCT patients? - answer Assess risk
factors, follow up testing (EKG, ECHO, labs such as BNP, A1c, thyroid function), medications,
weight loss, stress reduction
What is the major cause of transplant-related mortality and morbidity? - answer Infection-
related complication. Depends on hx of infections, chemo regimen intensity, and type of
transplant.
What are the risk factors of the development of an infection post-transplant? - answer -Hx of
infection (CMV status, blood stream infection)
-Type of transplant: Auto (regimen related) Allo (slow count recovery, GVHD)
-Myeloablative regimen and immunosuppression drugs
-HLA mismtached and CMV status
What are the prevention and management of infection? - answer -Vaccination (pneumococcus,
Tdap, Influenza, meningococcus, Hep B, MMR (1 year post)
, -Surveillance (T cell counts, CMV screening)
-Antibiotics Bactrim post transplant (6mo)
-Avoid pets
-Avoid sick people
-Practice good hygeine
-Safe sex practices
-Follow travel guidelines
What are other common post transplant complications? - answer -Occular
-Muscoskeletal
-Psychological
-Graft failure and rejection
What is the major cause of occular damage post transplant? What are the clinical
manifestations? - answer Cause: GVHD
Manifestations: Photophobia, conjuncitivits, ulceration, dryness, pain
What is the treatment for GVHD of the eyes? - answer -Cyclosporine eye drops
-Eye shielding during TBI
-Systemic immune suppression
-Lubricate the eyes
-Wearing eye protection
What is avascular necrosis (AVN)? - answer Painful condition that develops when blood supply
to the bone is disrupted
What are the risk factors of developing AVN? - answer -GVHD
-Old age
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller FREEMANSHARP. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £10.30. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
82871 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy revision notes and other study material for 14 years now