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WGU D027 Study Guide

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WGU D027 Study Guide

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  • December 5, 2023
  • 12
  • 2023/2024
  • Exam (elaborations)
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WGU D027 Study Guide
Autosomal Dominant - -1 parent has, 50% change of child having

-Autosomal Recessive - -Both parents are carriers, 25% change of child
having, 50% chance child is a carrier.

-Cystic Fibrosis - -affects pancreas causing secretions in lungs

-21st Trisomy - -Down Syndrome

-Klinefelter Syndrome (XXY) - -male has extra X, female like qualities

-Turner Syndrome - -Missing X in females

-Alpha Thalassemia - -inherited blood disorder; mild to severe anemia

-Beta Thallasemia - -low hemoglobin; contraindicated medication ferrous
sulfate

-Prevalence Risk - -proportion of the population affected at a certain time

-Incidence rate - -number of new cases divided by population

-Innate immunity - -inflammation; increased vascular permeability

-B&T lymphocytes - -immune response

-primary malignant tumor - -lack of organization of cells

-glucocorticoids - -used in combination with other agent to treat lymphoid
tissue (leukemia). glucocorticoids are directly toxic to lymphoid tissues.

-Selective estrogen receptor modulators (SERM) - -for hormone receptor
positive and advanced breast cancer. (Tamoxifin reduces risk and recurrence
risk)

-Heart failure - -impairment of the ventricle to fill with or eject blood; heart
cannot meet metabolic need of the body.

-CHF - -heart cannot keep up with metabolic needs; volume overload in
pulmonary area

-Left Ventricular Dysfunction - -reduced ejection fraction; ventricle having
issue ejecting blood.

, -normal ejection fraction - -55 - 60 % (blood pumped out with each
heartbeat)

-Ejection fraction of 50% - reduced or preserved? - -preserved

-Diastolic CHF - -preserved ejection fraction, problem is with filling

-Systolic CHF - -reduced ejection fraction, problem is with ejecting

-Left sided CHF - -pulmonary (JVD, fluid volume overload, rails, S-3
murmurs) ** #1 cause of Right sided CHF

-BNP - -gold standard lab test to diagnose CHF

-Echocardiogram - -Diagnostic tool, evaluates heart structure and function

-At Risk for HF - Stage A - -no structural heart disease or symptoms of heart
failure

-Stage A HF co-morbidities - -htn, atherosclerotic disease, diabetes,
metabolic syndrome, patients using cardiotoxins with family history

-Therapy goals of stage A HF - -treat htn, encourage smoking cessation,
encourage regular exercise, treat lipid disorders, discourage alcohol
intake/drug use, control metabolic syndrome
Meds: ACEI or Angiotensin II RB for vascular disease or diabetes (avapro,
losartan, benicar, diovan, etc)

-At Risk for HF - Stage B - -structural heart disease but no symptoms of
heart failure

-Stage B HF co-morbidities - -previous MI, LV remodeling with LV
hypertrophy and low EF, asymptomatic valvular disease

-Therapy goals of Stage B HF - -Meds: ACEI or ARB, Beta-blockers,
inplantable defibrillators

-Stage C heart failure - -structural heart disease with prior or current
symptoms of HF

-Presentation of Stage C HF - -known structural heart disease and shortness
of breath and fatigue, reduced exercise tolerance

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