Exam (elaborations)
WGU D027 Study Guide
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- WGU D027 Study Guide
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- WGU D027 Study Guide
WGU D027 Study Guide
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WGU D027 Study GuideAutosomal Dominant - -1 parent has, 50% change of child having
-Autosomal Recessive - -Both parents are carriers, 25% change of child
having, 50% chance child is a carrier.
-Cystic Fibrosis - -affects pancreas causing secretions in lungs
-21st Trisomy - -Down Syndrome
-Klinefelter Syndrome (XXY) - -male has extra X, female like qualities
-Turner Syndrome - -Missing X in females
-Alpha Thalassemia - -inherited blood disorder; mild to severe anemia
-Beta Thallasemia - -low hemoglobin; contraindicated medication ferrous
sulfate
-Prevalence Risk - -proportion of the population affected at a certain time
-Incidence rate - -number of new cases divided by population
-Innate immunity - -inflammation; increased vascular permeability
-B&T lymphocytes - -immune response
-primary malignant tumor - -lack of organization of cells
-glucocorticoids - -used in combination with other agent to treat lymphoid
tissue (leukemia). glucocorticoids are directly toxic to lymphoid tissues.
-Selective estrogen receptor modulators (SERM) - -for hormone receptor
positive and advanced breast cancer. (Tamoxifin reduces risk and recurrence
risk)
-Heart failure - -impairment of the ventricle to fill with or eject blood; heart
cannot meet metabolic need of the body.
-CHF - -heart cannot keep up with metabolic needs; volume overload in
pulmonary area
-Left Ventricular Dysfunction - -reduced ejection fraction; ventricle having
issue ejecting blood.
, -normal ejection fraction - -55 - 60 % (blood pumped out with each
heartbeat)
-Ejection fraction of 50% - reduced or preserved? - -preserved
-Diastolic CHF - -preserved ejection fraction, problem is with filling
-Systolic CHF - -reduced ejection fraction, problem is with ejecting
-Left sided CHF - -pulmonary (JVD, fluid volume overload, rails, S-3
murmurs) ** #1 cause of Right sided CHF
-BNP - -gold standard lab test to diagnose CHF
-Echocardiogram - -Diagnostic tool, evaluates heart structure and function
-At Risk for HF - Stage A - -no structural heart disease or symptoms of heart
failure
-Stage A HF co-morbidities - -htn, atherosclerotic disease, diabetes,
metabolic syndrome, patients using cardiotoxins with family history
-Therapy goals of stage A HF - -treat htn, encourage smoking cessation,
encourage regular exercise, treat lipid disorders, discourage alcohol
intake/drug use, control metabolic syndrome
Meds: ACEI or Angiotensin II RB for vascular disease or diabetes (avapro,
losartan, benicar, diovan, etc)
-At Risk for HF - Stage B - -structural heart disease but no symptoms of
heart failure
-Stage B HF co-morbidities - -previous MI, LV remodeling with LV
hypertrophy and low EF, asymptomatic valvular disease
-Therapy goals of Stage B HF - -Meds: ACEI or ARB, Beta-blockers,
inplantable defibrillators
-Stage C heart failure - -structural heart disease with prior or current
symptoms of HF
-Presentation of Stage C HF - -known structural heart disease and shortness
of breath and fatigue, reduced exercise tolerance
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