Comprehensive Basic Science Exam (CBSE) Review Set I Exam Questions With Correct Answers
3 views 0 purchase
Module
Cbse
Institution
Cbse
Chagas Disease - Answer Caused by Trypanosoma cruzi parasite passed in the feces of Reduviidae/kissing bug
Penetrates broken skin or intact mucous membranes forming a pseudocyst releasing inflammatory infiltrates into myocytes; stains with Giemsa & Wright
Romana sign occurs when portal of ent...
chagas disease caused by trypanosoma cruzi parasit
monocytes cell with half moon shaped nucleus that
Written for
Cbse
Cbse
Seller
Follow
Exampool
Reviews received
Content preview
Comprehensive Basic Science Exam (CBSE) Review Set I Exam Questions With Correct Answers Chagas Disease - Answer Caused by Trypanosoma cruzi parasite passed in the feces of Reduviidae/kissing
bug
Penetrates broken skin or intact mucous membranes forming a pseudocyst releasing inflammatory infiltrates into myocytes; stains with Giemsa & Wright
Romana sign occurs when portal of entry is the conjunctiva or eyelid May resulting in:
Enlarged heart- CHF, sudden cardiac arrest
Enlarged esophagus- difficulty swallowing
Enlarged colon- abdominal pain or constipation
Treat with benznidazole or nifurtimox
Monocytes - Answer cell with half-moon shaped nucleus that participates in phagocytosis
Chronic graft rejection - Answer multifactorial but typically involves arteriosclerosis
HLA-B27 - Answer PAIR:
Psoriasis
Ankylosing spondylitis- chronic synovitis destroying cartilage typically in young men
Inflammatory bowel dz- Crohn's & UC Reactive Arthritis-
Reactive Arthritis - Answer Arthritis as a reaction to a bacterial infection such as Campylobacter, Chlamydia, Salmonella, Shigella, or Ureaplasma.
Associated with conjunctivitis & uveitis
Gaucher (Type 1) - Answer AR Lysosomal storage disease Accumulation of sphingolipid glucocerebroside
Most common
Wrinkled tissue paper
I Cell disease - Answer Failure of Golgi apparatus to phosphorylate mannose 6-phosphate the marker to export enzymes to lysosomes resulting in accumulation of lysosomal enzymes in serum
Nitroblue tetrazolium test - Answer Aqualitative test to determine defects in NADPH oxidase
Negative: CGD
Positive: Acute Hepatitis, Mono
CGD (chronic granulomatous disease) - Answer inability to produce NADPH oxidase; susceptible to Cat + organisms; elevated neutrophils w/ normal T cell
Gp91 phox subunit: heme binding subunit of superoxide generating NADPH
Treat with interferon gamma Clarithromycin (macrolide) - Answer ADR of metallic taste & GI
Codeine - Answer ADR resp. depression, euphoria, & constipation
Cyclobenzaprine - Answer Structurally similar to TCAs w/ anticholinergic side effects used for relief of muscle spasms
May exacerbate glaucoma
Naproxen - Answer ADR of GI & renal (in elderly)
Timolol - Answer Used in HTN & glaucoma; ADR of bradycardia & worsening asthma
Bacterial vaginosis - Answer Sloughed mucosal cells = clue cells
Trichomoniasis - Answer Cilated, motile trophozoites w/ corkscrew-like motility
Autism - Answer Lack of eye contact, verbal communication, & separation anxiety; repetitious behavior
Emphysema - Answer Decreased FEV1/FVC ratio, normal FVC; TLC, FRC, & RV increase
Parathyroid hormone(PTH) vs phosphate in hypercalcemia - Answer PTH: rapid & direct
Phosphate: slow & indirect
ANP: - Answer Afib, Ch-1p, NPPA gene mutation causing binding interference,- decrease cGMP
Failure of development of 3rd or 4th pharyngeal pouches - Answer DiGeorge syndrome (CATCH 22): truncus arteriosus & agenesis of parathyroid glands
May also be associated w/ failure of thymus to develop -> T lymphocytes w/ CD3 marker Huntington disease - Answer PCR is the most common method to est. # of CAGs
Both the coding & template strands bind the forward & reverse primers on 3' end
Pyrmidine Dimers - Answer BRAF gain of function mutation causing covalant thymine (or Cystine) bonds normally repaired thru NER in the G1 phase by endonuclease recognition then excision (DNA polymerase
then fills; ligase then reseals)
Xeroderma pigmentosum - Answer Mutation of NER endonuclease from UV radiation disrupting DNA replication due to the oligonucleotides remaining damaged
DNA Polymerase I - Answer Removal of both leading & lagging RNA primers 5' to 3' (unique)
Proofreading of mismatch nucleotides via 3' to 5' exonuclease & elongation of lagging strand 5' to 3' (universal)
Topoisomerase - Answer Enzyme that functions in DNA replication, helping to relieve strain in the double
helix ahead of the replication fork.
Teniposide - Answer Topoisomerase II inhibitor acting in the S phase & G2 phase:
S phase: prevents proper unwinding of supercoils & reannealing of DNA
G phase: Permanent breaks in both strands of DNA preventing transcription & repair inducing cell cycle arrest
Cytarabine - Answer Antimetabolite inhibiting DNA polymerase, arresting cells solely in S phase
Fluoroquinolones ( -floxacin) - Answer Bactercidal: direct inhibition of topoisomerase 2 & 4 halting DNA replication as 1st line treatment of uncomplicated pyelonephritis; older for gram negative & aerobic, newer more broad spectrum
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Exampool. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £10.63. You're not tied to anything after your purchase.
