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Lecture notes

Neuroanatomy of the cerebellum

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Each concept is accompanied by vivid diagrams and illustrations, making it easier to visualize and understand the brain's intricate structures. Complex topics are broken down into digestible segments, making it easier to grasp difficult concepts and retain information longer. Organized logically, w...

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  • January 15, 2024
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  • 2023/2024
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Cerebellum
The cerebellum originates from the dorsal aspect of the brainstem and overlies the fourth ventricle. The cerebellum is connected to the brainstem
by three pairs of fibers bundles – inferior, middle, and superior cerebellar peduncles. They join the cerebellum to the medulla, pons, and midbrain
respectively. The cerebellum carries motor function and its function at unconscious level. It maintains equilibrium (balance), and influences posture,
muscle tone and coordinates movement.
• External features of the cerebellum - Figure 1 and 2
The cerebellum is made of two laterally located
hemispheres, which is joined by vermis in the
midline. The superior part of the cerebellum is
located beneath the dural tentorium and superior
vermis is raised forming a midline ridge. The inferior
vermis is located in the deep groove between the
hemispheres. The cerebellum surface is very
convoluted creating folia. Between the folia there is
deep fissures, and they are used to divide the
cerebellum, into three lobes. On the superior part Figure 1. Lateral aspect of the brainstem and cerebellar, showing the cerebellar peduncle.


of the cerebellum the deep primary fissure separates small anterior lobe from
posterior lobe. On the underside, the conspicuous posterolateral fissure marks the
location of small regions of the hemisphere (the flocculus) and vermis (the nodule)
which together form the flocculonodular node.

• Internal structure of the cerebellum
The cerebellum is made of outer layer is made of grey matter, the cerebellar
cortex, and inner part of the cerebellar white matter. The white matter is made of
afferent and efferent fibers that project to and from cortex. Deep in the white
matter there are four bilaterally cerebellar nuclei which have output fibers,
creating connections with the cerebral cortex and some certain nuclei of the
brainstem and thalamus.

• Cerebellar cortex – Figure 7
The cortex contains cell bodies, dendrites, and synaptic connections. The cerebellar
cortex is divided into the outer molecular layer, the intermediate Purkinje cell
layer, the inner granular layer which is dominated by the granule cell.
Afferent projections to the cerebellum from a spinal cord (spinocerebellar
fibers), inferior olivary nucleus (vestibulocochlear fibers) and pons
(pontocerebellar fibers). Afferent fibers synapse in the cerebellar cortex, fibers
then enter the cerebellum through one of cerebellar peduncles and then course to
the cortex as either mossy fibers or climbing fibers.
Afferent fibers that originate elsewhere from the inferior olivary nucleus end as
mossy fibers. Mossy fibers supply several folia and end in the granular layer. Figure 2. Superior surface of the cerebellum




Figure 3. Posterior aspect of the cerebellum.
Figure 4. Anteroinferior aspect of the cerebellum.

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