Malate can be converted to pyruvate in the cytosol. Which of the following
compounds is directly generated in this conversion and is essential for fatty
acid synthesis?
FADH2
ATP
Acetyl-CoA
NADPH Correct Ans - NADPH
An increase in the ratio of insulin to glucagon will increase the activity of
which of the following enzymes (+ indicates activity is increased; -
indicates activity is not increased by insulin)?
Which of the following enzymes is correctly paired with its allosteric
inhibitor?
Pyruvate dehydrogenase complex: pyruvate
Pyruvate kinase: fructose 1,6-bisphosphate
Carnitine palmitoyl transferase I: acetyl-CoA
Acetyl-CoA carboxylase: palmitoyl-CoA Correct Ans - Acetyl-CoA
carboxylase: palmitoyl-CoA
Under conditions when glucose oxidation is elevated, the acetyl-CoA
produced will allosterically activate which of the following enzymes
leading to an increase in the production of oxaloacetate?
Pyruvate carboxylase
Citrate lyase
Acetyl-CoA carboxylase
Malate dehydrogenase Correct Ans - pyruvate carboxylase
, Fatty acid synthase is a multimeric enzyme complex. Which of the
following subunits contains pantothenic acid as a cofactor?
Ketoacyl synthase
Acyl carrier protein (ACP)
Thioesterase
Enoyl reductase Correct Ans - Acyl carrier protein (ACP)
NADPH is essential for fatty acid synthesis and can be generated by which
two enzymes? (+ indicates NADPH can be produced by the enzyme; -
indicates the enzyme does not produce NAPDH)
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