UNE Medical Biochemistry Unit 2 Test – Questions With
Solutions
If unregulated, which of the following pairs of enzymes would represent a
futile cycle? Correct Ans - Fructose 1,6 bisphosphatase and
phosphofructokinase-1
Rotenone blocks complex 1 in the ETC. This increases levels of NADH and
would likely impair the function of which of the following enzymes?
Correct Ans - Pyruvate dehydrogenase complex
Newborn screening shows a biotinidase deficiency in a 2-day old infant.
This deficienty impairs the infant's ability to reuse and recycle biotin. Due
to this enzymatic deficiency, the activity of which of the following enzymes
is likely impaired? Correct Ans - pyruvate carboxylase
An individual is recently diagnosed with Type 2 diabetes. In this individual,
hyperglycemia may in part be due to inactivity of which of the following
glucose transporters on skeletal muscle? Correct Ans - Glut 4
(insulin dependent)
The skeletal muscle primarily provides substrate for gluconeogenesis
through which of the following processes? Correct Ans - protein
catabolism
Alanine can be shuttled from the skeletal muscle to the liver where it is
deaminated to produce pyruvate. When glucagon is high, pyruvate is
primarily used as a substrate for which of the following pathways?
Correct Ans - gluconeogenesis
Aldolase B facilitaes a reaction that cleaves fructose 1-phosphate into two
3-carbon molecules that will enter glycolysis as which of the following
compounds? Correct Ans - glyceraldehyde-3-phosphate
Within the RBC, NADPH is used for which of the following processes?
Correct Ans - to re-reduce glutathione
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