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Exam (elaborations)

NBME Question and Answers with Approved solutions

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NBME Why an deoxy. blood carry more CO2 for a given PCO2 than oxy blood? - ANSW Deoxy Hb is a better buffer of H ions than oxy Hb due to Haldane effect in lungs What method should be used to identify clusters of differentiation (e.g. CD44)? - ANSW Immunohistochemistry (checks surface prot...

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  • February 15, 2024
  • 14
  • 2023/2024
  • Exam (elaborations)
  • Questions & answers
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NBME

Why an deoxy. blood carry more CO2 for a given PCO2 than oxy blood? - ANSW
Deoxy Hb is a better buffer of H ions than oxy Hb due to Haldane effect in lungs

What method should be used to identify clusters of differentiation (e.g. CD44)? - ANSW
Immunohistochemistry (checks surface proteins expressed by cells)

*REMEMBER: PCR does not equal ELISA lol - PCR identifies DNA sequences

Pancreatic cancer is associated w/ what behavioral change? - ANSW Major
depressive disorder - apparently there is an association between this one especially w/
MDD because of its poor prognosis

*I thought scientifically and put personality change thinking like kernicterus lol but i dont
htink jaundice goes to brain in adults

What is zanamivir? - ANSW A neuraminidase inhibitor

Subependymal astrocytomas, seizures, and a cardiac rhabdomyoma are associated w/
which neurocutaneous disorder? - ANSW Tuberous sclerosis

52 y.o man with 3 days blindness of the left eye. No pain. Fundoscopy of left eye show
pale opaque fundus and bright red fovea centralis. Dense scotoma of entire visual field
of the left eye. Right eye no abnormalities. 6 months later (still blind in elft eye), what will
be the response of the R. pupil if the L. eye is illuminated? - ANSW No constriction
because retinal ganglion ells in left eye have been destroyed

*CN II is no longer working

An 18 month old boy w/ SCID needs a blood transfusion for severe anemia - what type
of blood do we give him? - ANSW Irradiated packed RBCs

Hydronephrosis on gross imaging in a 17 y.o. boy - ANSW

The empty can test tests what muscle? - ANSW Supraspinatus muscle + tendon

From supine to standing, how are venous return, carotid sinus baroreceptor activity, and
CBF affected? - ANSW All decrease

1/10 of a man's sperm contain a mutation for type 1 procollagen associated w/
osteogenesis imperfecta - what's the explanation for this? - ANSW Germline
mosaicism

, Woman refuses to take ibuprofen for her joint paints and asks about glucosamine - what
do you do? - ANSW Ask her to tell you what you heard about using glucosamine to
treat arthritis

I picked that its side effects aren't listed and it may be more dangerous than we realize

Vitamin C deficiency leads to what problem in collagen synthesis? - ANSW Inadequate
hydroxylation of collagen polypeptides

I got this right - I am just reinforcing it

Hypertrophied heart...What is the normal weight of the heart? - ANSW See NBME 15
Block 2 question 42 for pic

250-350g

Howcome during a series of normal skeletal muscle twitches, ATP concentration doesn't
fall appreciably? - ANSW ATP is quickly regenerated from creatine phosphate

*normal metabolism can't produce energy as quickly as a muscle can use it so creatine
phosphate acts as an extra storage source

Palpable mass in the posterior aspect of labium majus is likely what?

Blood and urine cultures are negative for pathogens - ANSW Bartholin gland cyst
(infection of the greater vestibular (Bartholin) gland)

Where does the cervix drain into? - ANSW Internal iliac

In what types of shock do you have cool extremities? - ANSW Hypovolemic,
cardiogenic, and obstructive

*only one you have warm extremities in is distributive e.g. sepsis

Where is Wernicke's area on an image? - ANSW I put it way more anterior and lower!!
lol it was a brain labeled w/ A B C etc and I knew it was Wernickes - I just localized it
wrong

Cocaine use puts a fetus at risk of what? - ANSW Prematurity, IUGR etc

Not heart defects

Extravascular accumulation of fluid after a bee sting is due to what change in the
endothelium? - ANSW Gap formation between endothelial cells

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