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Summary

Summary YR 2 CONTENT

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Summary of 4 pages for the course Foundations Of Biomedical, Behavioural And Social Sciences For Medicine 2020/21 at UoS (YR 2 CONTENT)

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  • February 19, 2024
  • 4
  • 2023/2024
  • Summary
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Infection as a mechanism of disease
● Infection: colonisation of a pathogenic species, utilise the hosts resources to
reproduce and produce disease
● Caused by: viruses,bacteria,fungi,parasites

● Classified by symptoms,causative agent, medical signs

Symptoms=apparent infection
No symptoms= silent,subclinical

Inactive/dormant=latent

Principles of infection:
● Susceptibile host

● Host resistance

● Virulence and pathogenicity

● Control and transmission

Exogenously- bacteria in the environment
Endogenously-bacteria on ourselves-normal flora, injuries on skin

Routes of infection:
● Skin- keratinized barrier,low
pH,commensals
● Hair

● Eyes- fluid,eyelashes

● Respiratory- alveolar
macrophages,air flow,cilia,secretions
● GI- M cells, acid,secretions,bile,mucus

● GU-e,commensals

● Urinary tract-flushing,mucus,commensals

Direct/indirect contact
● Faecal-oral

● Sexually transmitted

● Verticle

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