BCPS Test Questions with All Correct Answers sensitivity formula - ANSWER "Sensitivity =true positive/(true positive +false negative) Note: more sensitive is closer to 1" specificity formula - ANSWER Specificity = True negative/(true negative + false positive) precision definition - ANSWER how consistent the test results are accuracy formula - ANSWER "accuracy=(true positive plus true negative)/total - how true the test results are" receiver operator characteristic - ANSWER "the cutoff value for maximizing accuracy; describes the inverse relationship between sensitivity and specificity (i.e. increasing specificity decreases sensitivity)" positive predictive value for mula - ANSWER PPV=True positive/(true positive +false positive) negative predictive value formula - ANSWER NPV= true negative/(true negative + false negative) prevalence definition - ANSWER total number of cases at a give n time incidence definition - ANSWER new cases in a specfiic time peiod likelihood ratio formula - ANSWER "positive test =true positive %/ false positive% OR negative test =false negative %/true negative % " when is a 95% CI statis tically significant - ANSWER "for mean: if it doesn't cross 0; For OR/RR, if it doesn't cross 1" When is RR done - ANSWER prospective studies When is OR done - ANSWER retrospective studies (would overestimate the risk in prospective studies unless incidence in population is <10%) RR formula - ANSWER RR=incidence rate in exposed patients/ incidence rate in non-exposed patients if RR >1, what does that mean - ANSWER the incidence in the exposed group is higher than non -exposed group Odds Ratio Formula - ANSWER OR = (# of exposed with disease present X # of unexposed with disease absent)/(# of exposed with disease absent x # of unexposed with disease present) what looks at predictability? - ANSWER regression analysis, not correlation coefficient coefficient of variation (r squared) definition - ANSWER this provides us with the %of information we can attribute from one variable to another linear regression vs multilinear regression - ANSWER linear is 1:1 independent to dependent variables, whereas multilinear is multiple:1 independient to dependent variables logistic regression analysis - ANSWER done to determine whi ch variables are important to predicting the outcome Therapeutic Index Formula - ANSWER TI= median toxic (lethal) dose/median effective dose Drug interaction with protease inhibitors - ANSWER Inhibit CYP3A4 NNRTI that inhibits not induces - ANSWER delavridine what SNP is a problem with carbamazepine - ANSWER HLA -B*1502 what SNP is a problem with abacavir - ANSWER HLA -B*5701 more potent isomer of warfarin; cyp it goes - ANSWER S -isomer; 2C9 less potent isomer of warfarin; Cyp it goes through - ANSWER R -isomer; 3A4 inhibitors of 2C9 (4 A, S, M, F) - ANSWER Amiodarone, SMX/TMP, metronidazole, Fluconazole what cyp is most important for clopidogrel activation - ANSWER 2C19 Which PPIs inhibit Cyp 2C19 - ANSWER omeprazole, lansoprazole diltiazem/verapamil's mechanis of drug interactions (2) - ANSWER 3a4, Pgp
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller oldGold. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £9.86. You're not tied to anything after your purchase.
