NR565 / NR 565: Advanced Pharmacology Fundamentals
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NR 565 Midterm Exam
1.What are medication examples of Schedule II drugs
ANS -Ativan & Valium
-Fentanyl
-Oxycodone
-Methadone
2.What medications are Schedule III drugs
ANS -Xanax
-Tramadol
-anabolic steroids
-<90mg of codeine
3.What medications are Schedule IV drugs
ANS -Ativan
-Tramadol
-Methadone
-Adderall
4.Which schedule drugs can APRNs prescribe
ANS Schedule II through Schedule IV
5.examples of reasons for medication non-adherence ANS -too busy
-too expensive
-ran out
-forgetting
-traveling & busy
6.Distribution in medication in elderly can be affected in what ways
ANS -de- creased lean mass
-decreased albumin
-decreased body fat
-slower gastric acidity
-slower absorption results in delayed response
7.In the elderly decrease albumin and decreased lean mass affects medica- tions how
ANS medication binds to protein so decreased protein affects how medica- tion is absorbed and distributed
8.In elderly decreased body fat affects medications how
ANS need fat to transport medications and some drug metabolism is dependent on body weight
9.When prescribing medication, we must understand that liver function de- clines with age due to....
ANS decreased blood flow to the liver, decreased hepatic enzymes
10.What is the most important cause of adverse drug reactions
ANS ***overpre- scribing/polypharmacy
***decreased renal excretion
-high drug dosages (start low & go slow)
-lack of monitoring medications .What can a poor metabolism phenotype do to a metabolism of a drug
ANS -
-slow or increase absorption
-slow the metabolism
-keep drug in body longer
-increase toxicity
12.How does poor metabolism affect a high or low therapeutic index
ANS -in- crease drug toxicity
(example plavix - clots & increased platelets)
13.Black box warning for Opioids
ANS respiratory depression
14.Black box warning for Fentanyl
ANS FATAL respiratory depression
15.Black box warning for Methadone (NP cannot prescribe)
ANS QT interval prolon- gation
16.Black box warning for Codeine
ANS -breastfeeding and infant death can occur
-10% of dose converts to morphine
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