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Sumario Resumen de metabolismo de aminoácidos
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Resumen de Química de metabolismo de aminoácidos
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Metabolismo de AminoacidosFUNCIONES DESTINO DE Aa
- Catalizadoras de reacciones qcas→ ENZIMAS HC, y Lípidos se almacenan ≠ Aa circulan en sangre
- Reguladores d actividades celulares→ HORMONAS
- Transporte en sangre→ HEMOGLOBINA y otras Pool/ Fondo común: conj de Aa libre en sangre para síntesis de
- Defensa natural→ ANTICUERPOS nuevos compuestos.
- Receptores celulares→ APOPROTEINAS
- Acortamiento muscular en contracción→ ACTINA Y MIOSINA
- Integran fibras en tejido de sostén→ COLAGENO
- Función energ→ Secundaria y reemplazable x HC y Lípidos
CATABOLISMO DE Aa
- Inician su degradación c separación d grupo α- amino del
esqueleto carbonado
-Vias Metabólicas Específicas:
* transaminación→ Reacciones de transferenci
Digestión de Aa
Cav. Bucal: no hay enzima
Estómago:
HCl → desnaturaliza
Pepsina (endo) escine
segmentos de alto peso molec.
Intestino(duodeno):
→ Borde en cepillo:
ENDOPEPTIDASAS: Enteroquinasa del tripsinogeno y otras q actuan
PRINCIPALES REACCIONES DE IMPORTANCIA CLÍNICA:
sobre oligopeptidos.
→ Todas forman Glutamato + moleculas
EXOPEPTIDASAS: Aminopept. Y Dipeptid.
→ x jugo pancreatico
GTP: CITOPLASMA de HÍGADO, CORAZÓN y MÚSCULO.
ENDOPEPTIDASAS→ Aa libres
GOT: MITOCONDRIA y CITOPLASMA de HIGADO y CORAZÓN
EXOPEPTIDASAS→ dipeptidos y tripeptidos→ hidrolizadoa Aa libre x
enterocitos
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