Exam (elaborations)
NUR 321- cellular regulation
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- 4.ED FORMS - Verbs Or Modifiers.
NUR 321- cellular regulation
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NUR 321- cellular regulationhow does cyclophosphamide work and what is the NADIR? - ANS-Action: Causes the
cross link and strand breakage which prevents replication of the cancer cell
NADIR: Leukocytes 2-12; thrombocytes 10-15
what are some adverse reactions associated with glucocorticoids? - ANS-Osteoporosis
Adrenal insufficiency
Increased risk of infection
GI ulcerations (bleeding)
Delay growth in children
Thin skin
Increase glucose
what are the additional benefits of glucocorticoids? - ANS-Additional Benefits: Decrease
N/V, decrease swelling/edema, decrease nerve pain, increase appetite, gain weight
what are the adverse reactions and NADIR of vincristine? - ANS-Ascending peripheral
neuropathy
Little to no effect on bone marrow
Hepatotoxicity
Nadir: 4 days
what are the adverse reactions and the NADIR of doxorubicin? -
ANS-Cardiotoxic-cardiomyopathy
Normal adverse reaction- Turns the urine red/orange
NADIR: 10-14 days
what are the adverse reactions and the Nadir of methotrexate? - ANS-GI and oral
ulcerations
Hemorrhagic enteritis
Pulmonary infiltrates and fibrosis
nadir: 7-14 days
what are the adverse reactions of cyclophosphamide? - ANS-Hematuria from
hemorrhagic cystitis
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