Exam (elaborations)
MCB 2010 Chapter 17
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- NUR 240 EXAM 2 Practice Questions.
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MCB 2010 Chapter 17A new chemical messenger has been discovered that enhances the chemotaxis of
macrophages and neutrophils toward sites of infection. It would be specifically classified
as a/an - ANS-chemokine
A property of T cells, but not B cells, is their - ANS-ability to form cells that directly kill
virus-infected host cells
Acquired Immunity - ANS-the ability obtained during the life of an individual to produce
specific antibodies.
Activation of complement - ANS-Causes inflamation and cell lysis IgG or IgM
ADCC - ANS-the killing of antibody coated cells by natural killer cells and phagocytes.
Agglutination - ANS-a joining together or clumpling of cells
Agglutination - ANS-reduces the number of infectious units to be dealt with. IgM
Antibodies - ANS-An antigen-binding immunoglobulin, produced by B cells, that
functions as the effector in an immune response. Made by leukocites
Antibody - ANS-a protein produced by the body in response to an antigen, and capable
of combining specifically with that antigen.
Antibody dependent cell mediated cytotoxicity - ANS-Antibodies attached to target cell
causes destruction by macrophages, eosonophils and NK cells. Sometimes using
Perforin and lycti enzymes.
Antibody dependent cell mediated cytotoxicity - ANS-Organisms, such as many
parasites that are too large for ingestion by phagocytic cells must be attacked externally.
Includes cytotoxic cytokines, Lytic enzymes and Perforin enzymes.
Antibody titer - ANS-the amount of antibody in serum
Antibody-dependent cell-mediated immunity - ANS-operates against large pathogens
such as parasitic protozoa and worms.
, antigen - ANS-any substance that causes antibody formation and reacts only with its
specific antibody, also called immunogen.
Antigen Antibody binding - ANS-AB binds epitope. Can distinguish between isomers.
Antigen-antibody complex - ANS-the combination of an antigen with the antibody that is
specific for it, the basis of immune protection and many diagnostic tests.
Antigenic Determinant - ANS-a specific region on the surface of an antigen against
which antibodies are formed, also called Epitope.
Antigens - ANS-could be proteins or large polysaccharides
Antigens components on cell wall - ANS-recognize and interact with epitopes
APC - ANS-A macrophage or dendritic cell that engulfs an antigen and presents
fragments to T cells
APCs - ANS-macrophage, dendritic cell, B cell, antigen Presenting Cells
Artificial acquired passive immunity - ANS-the transfer of humoral antibodies formed by
one individual to a susceptible individua, accomplished by the injection of antiserum.
Artificially Acquired Active Immunity - ANS-the production of antibodies by the body in
response to a vaccination
B cell - ANS-a type of lymphocyte, differentiates into antibody secreting plasma cells
and memory cells.
B cells - ANS-do not participate in a cell-mediated immune response.
B-cell activation Step 1 - ANS-Immunoglobin receptors on B cell surface recognize and
attach to antigen. It is then internalized and process. Within B cell a fragment of the
antigen combines with MCH Class II
B-cell activation Step 2 - ANS-MHC class II antigen fragment comples is displayed on B
cell surface
B-cell activation Step 4 - ANS-B cell is activated by cytokines and begins clonal
expansion. Some of the progeny become antibody producing plasma cells.
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