100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Previously searched by you
Previously searched by you
logo
Summary Therapeutic index explained £3.62   Add to cart
Quickly navigate to
Preview
  2.  
  3. University Of Pretoria (UP)
  4.  
  5. Pharmacology

Summary

Summary Therapeutic index explained
 51 views  0 purchase
  • Module
  • Pharmacology
  • Institution
  • University Of Pretoria (UP)
  • Book
  • Rang & Dale\'s Pharmacology

I want to help you get through all the different drug classes in Pharmacology. I have found that students struggle to get through the amount of work. These summaries helped me get through my Honours Degree. I will soon graduate with my Masters of Science in Neurogenetics. You got this!

Preview 1 out of 1  pages

Document information

  • Yes
  • June 19, 2019
  • 1
  • 2014/2015
  • Summary

Subjects

  • therapeutic index
  • pharmacology
  • ti

Connected book

book image

Book Title:

Author(s):

  • Edition:
  • ISBN:
  • Edition:

More summaries for

  • principles of pharmacology
  • Ionisation Explained
  • Drug action on sites explained
All for this textbook (18)

Written for

  • University of Pretoria (UP)
  • Pharmacology
All documents for this subject (17)

Seller

avatar-seller
chanbain

Content preview

Class Drug Indications General Adverse reactions DIs
Colchicine  ↓ risk of flares (NOT joint  Diarrhea  Erythromycin
damage)  Nausea  Simvastatin
 ONLY when NSAIDS are CI  Myelosuppresion  Cyclosporin
 ↓ clearance in renal failure  Myopathy
(danger, renal impairment)  Rabdomyolysis
 Not 1st line due to severe AEs  Renal failure

Urate Allopurinol  Frequent attacks  Purine analogs
lowering  Tophaceous gout  Inhibits XO
 Gout with renal failure  Substrates of XO
 Recurrent stones  Thus blocking
 High serum urate levels hypoxanthinexanthineuric
(males 0.77Um/l, females acid
0.59Um/l)
 Urinary urate = >
6.5mmol/day

Newer Febuxostat  Treatment of chronic  Selective XO inhibitor  Liver toxicity?
therapies hyperuricaemia (conditions  Minimal excretion in the urine
where urate deposits has  Can administer in renal
already occurred) insufficiency and mild/moderate
 Management of chronic hepatic insufficiency with no
hyperuricaemia in gout in dosage adjustments
allopurinol is not tolerated or
CI

Uricosuric  Probenecid Mild uricosuric agents:
agents  Benzbromar  Losartan (Cozaar)
one (ex-US)  Fenofibrate
 Sulfinpyrazo
ne (ex-US)

Recombinan Rasburicase Recombinant porcine-like Pegloticase  ↓ risk of
t urate uricase Metabolizes: precipitates
oxidase Ric  Treat resistant gout
acidallantoin(m
ore soluble)

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller chanbain. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for £3.62. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

73918 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy revision notes and other study material for 14 years now

Start selling
£3.62
  • (0)
  Add to cart