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UNMC Nursing Pathophysiology 2 Exam 4.

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UNMC Nursing Pathophysiology 2 Exam 4.

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  • June 11, 2024
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  • 2023/2024
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UNMC Nursing Pathophysiology 2 Exam 4
pH ratio - ANS-bicarbonate/carbonic acid (base/acid)

Three Mechanisms Regulating Acid-Base Balance - ANS-1. Plasma buffer system
2. Respiratory system
3. Renal system

Plasma buffer systems - ANS-work fast!
-HCO3-, H2CO3
-protein buffers
-phosphate
-cellular ion exchange mechanism

How does the respiratory system regulate acid-base balance? - ANS-Regulate retention
or elimination of CO2 through changes in rate of ventilation.

How does the renal system regulate acid-base balance? - ANS-kidneys either reabsorb
or secrete more bicarbonate or hydrogen ions

normal blood pH - ANS-7.35-7.45

normal pCO2 - ANS-35-45

normal HCO3 - ANS-22-28

Etiology of respiratory acidosis - ANS-anything depressing ventilation or gas exchange,
respiratory disorder, lung disease

Initial ABGs respiratory acidosis - ANS-pH: Low (<7.35)
pCO2: High (>45)
HCO3: Normal (22-28)

Compensated ABGs respiratory acidosis - ANS-pH: on the low end of normal
(7.35-7.40)
pCO2: High (>45)
HCO3: High (>28)

, How is respiratory acidosis corrected? - ANS-by kidneys= retain (reabsorb) more
HCO3- and excrete H+

Respiratory alkalosis etiology - ANS-hyperventilation (blowing off too much CO2)

Initial ABGs respiratory alkalosis - ANS-pH: High (>7.45)
pCO2: Low (<35)
HCO3: Normal (22-28)

Compensation in respiratory alkalosis - ANS-By kidneys, retain (reabsorb) more H+ and
excrete more HCO3-

Compensated ABGs respiratory alkalosis - ANS-pH: on the high end of normal
(7.40-7.45)
pCO2: Low (<35)
HCO3: Low (<22)

Metabolic acidosis etiology (5) - ANS-loss of base or gain of acid
1. renal failure (unable to retain HCO3-)
2. lactic acidosis
3. Diabetic ketoacidosis
4. diarrhea
5. ingestion of acids

Initial ABGs metabolic acidosis - ANS-pH: Low (<7.34)
pCO2: Normal (35-45)
HCO3: Low (<22)

Compensation in metabolic acidosis - ANS-By lungs, hyperventilate to blow off acidic
CO2 (Kussmall's)

Compensated ABGs metabolic acidosis - ANS-pH: on the low end of normal (7.35-7.40)
pCO2: Low (<35)
HCO3: Low (<22)

Metabolic alkalosis etiology - ANS-loss of metabolic acids, excess HCO3- intake

Initial ABGs metabolic alkalosis - ANS-pH: High (>7.45)
pCO2: Normal (35-45)
HCO3: High (>28)

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