100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Previously searched by you
Previously searched by you
logo
GNUR 203 Module 7. £7.16   Add to cart
Quickly navigate to
Preview
  2.  
  3. Anatomy Condensed Final Exam Review - GNUR 155
  4.  
  5. Anatomy Condensed Final Exam Review - GNUR 155
  6.  
  7. Anatomy Condensed Final Exam Review - GNUR 155

Exam (elaborations)

GNUR 203 Module 7.
 2 views  0 purchase

Exam of 6 pages for the course Anatomy Condensed Final Exam Review - GNUR 155 at Anatomy Condensed Final Exam Review - GNUR 155 (GNUR 203 Module 7.)

Preview 2 out of 6  pages

Document information

  • June 15, 2024
  • 6
  • 2023/2024
  • Exam (elaborations)
  • Questions & answers

Subjects

Written for

All documents for this subject (53)

Seller

avatar-seller
denicetho

Content preview

GNUR 203 Module 7
Antimicrobial resistance - ANS-microbe isn't affect by a drug therapy that is intended to
inhibit or eliminate the pathogen

What are superbugs? - ANS-resistant microbes

Intrinsic Resistance - ANS-natural resistance to antimicrobial drugs

How is intrinsic resistance developed? - ANS-pathogens gain this through mutations of
DNA

What are the 4 mechanisms of antimicrobial resistance? - ANS--alter drug target: the
target is changed in cell so drug does not bind anymore
-reduced permeability: low concentration inside the cell and endospores and mycolic
acid prevent drug from going into the cell
-pump drug: the cell goes through a fast removal process of the drug
-alter drug: the drug shape is changed and does not allow for binding on the target

How do resistant populations develop? - ANS-The last cell to die is the most resistant, if
it does not die then it goes through binary fission and cloning and creates a new
resistant population

Acquired resistance - ANS--from acquiring genes from another microorganism
-faster than intrinsic resistance

How does acquired resistance work? - ANS-genes from other microorganism are
contained on an R-plasmid and transferred to another microorganism

Vertical gene transfer - ANS--cell passes genetic info to next generation because of cell
division
-human cells

Horizontal gene transfer - ANS--cell passes genetic info between cells through
independent cell division
-bacteria cells

What is required for horizontal gene transfer? - ANS-F-plasmid that encodes the pilus
which allows for transfer of this to another cell that is lacking it

, R-Plasmids - ANS-antimicrobial resistant genes

F-plasmids - ANS-genes that allow transfer of plasmid

F and R plasmids - ANS-antimicrobial resistant genes and genes necessary for
transferring the plasmid

Why does acquired resistance allow for bacteria to become resistant to multiple drugs?
- ANS-they can obtain multiple R-plasmids which will allow for the development of
resistance to multiple drugs

What enzyme allows for resistance to B-lactams? - ANS-B-lactamase

How does B-lactamase work? - ANS--breaks dow B-lactam ring which prevents
functioning of the drug
-allows for cross-bridges to form allowing resistance to B-lactams

What are the 3 organisms that the CDC classifies as an urgent threat? -
ANS--Clostridioides difficile
-Carbapenem-resistant Enterobacteriaceae
-Drug-resistant Neisseria gonorrhoeae

What is CRE? - ANS--carbapenem-resistant enterobacteriaceae
-group of enterobacteriaceae that have become resistant to carbapenems and other
common antibacterial drugs
-it is a resident microbiota
-it is not a pathogen

Where can you find CRE? - ANS-member of the microbiome of the human GI system

How does CRE cause disease? - ANS-they can spread outside of the GI system and
act as opportunistic pathogens

How is CRE transmitted? - ANS--through direct and indirect contact
-hands of healthcare workers

Why is CRE classified as an urgent threat? - ANS-some strains are resistant to almost
all available antibiotics so there's no way to treat

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller denicetho. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for £7.16. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

76449 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy revision notes and other study material for 14 years now

Start selling
£7.16
  • (0)
  Add to cart