NR 565 Midterm - week 3 & 4
Acute flair of gout - correct answer-NSAID or Colchicine - comparable to other agents if
taken within 24 hours.
ASCVD risk - correct answer-elevated LDL over or equal to 90 mg/dl, 40-75 years of age
with diabetes and LDL 70-189, and ASCVD risk score of 7.5% or higher.
Atherosclerotic Cardiovascular Disease - correct answer-developed by the American college
of cardiology and calculates 10 year risk of having heart attack or stroke. Takes into account
age, sex, race, cholesterol levels, BP, medication use, diabetic status, and smoking.
BB & asthma - correct answer-can increase bronchial obstruction and airway. can
exacerbate asthma.
Beta Blockers - olol - correct answer-decreases cardiac oxygen demand through blockade of
specific receptors in the heart. Their use with nitroglycerin and reflective tachycardia can
combine to combat it.
Carbamazepine (ARB) - correct answer-if prescribed with warfarin - carbamazepine
decrease the effects of warfarin and should be monitored closely.
Cholesterol Absorption Inhibitor - non statin therapy - correct answer-Ezetimibe (Zetia) -
prescribed when patients do not achieve satisfactory LDL reduction or cannot tolerate a
statin
Colchinicine - correct answer-anti inflammatory agent with effects specific for gout. however,
common occurrence of GI toxicity - can be used short term to treat acute gouty attack or
long term to prevent attacks from recurring.
complications of untreated gout - correct answer-symptoms result from the deposition of uric
acid crystals in joints.
Contraindications for Ranolazine - correct answer-renal failure, liver cirrhosis, taking CYP3A
inhibitor and inducer.
Contraindications for statins - correct answer-pregnancy, viral or alcoholic hepatitis, avoid
use in children under 10
contraindications to thiazides - correct answer-sulfa allergies, use in caution with patients
with cardiovascular disease, renal impairment, diabetes, or a history of gout. Pt. taking
digoxin, lithium, or antihypertensive drugs.
Digoxin - correct answer-only cardiac glycoside that is available in the United States. Exerts
a positive inotropic action on the heart
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