Activated partial thromboplastin time (aPTT) - correct answer-Screens for intrinsic and
common pathways
- all Factors except VII and XIII
- Monitor Heparin therapy
-Reagent: Activator (kaolin, celite or ellagic acid), platelet phospholipid and CaCl2
RI: 25-35seconds
Therapeutic goal: 1.5-2.5 * normal
Acute blood Los - correct answer-Normocytic/Normochromic anemia
Normal BM, increased retics
Acute Lymphocytic Leukemia (ALL) and Lymphoma - correct answer-A. Classified as same
disease with different clinical presentations
B. Either B or T according to cell lineage
C. Peripheral blood and BM involvement with>20% blasts defines ALL
D. Solid tumor presentation defines lyphoma
Adult Hematopoiesis - correct answer-Skull, sternum, pelvis, ribs and vertebrae.
Flat bones: active adult hemopoietic tissue (colony forming units in red marrow)
,Alder-Reilly Anomaly - correct answer-Characteristics: Large azurophilic granules
Antiphospholipid syndrome - correct answer-Any of the three classes of antibodies.
Anticardiolipin antibodies. Lupus anticoagulant. Specific antibodies.
Antithrombin - correct answer--Principle antagonist of active coagulation proteases.
---Produced in the liver.
-Activated by heparin sulfate on the endothelial cell and by heparin as a therapeutic drug.
Aplastic Anemia - correct answer-a normocytic-normochromic type of anemia characterized
by the failure of bone marrow to produce red blood cells
- Dry Tap bone marrow, hypocellular BM, decreased retics, pancytopenia
N-Increased serum ferritin, Decreased serum Iron
Decreased TIBC
Chronic Lymphocytic Leukemia (CLL) - correct answer-abnormal numbers of relatively
mature lymphocytes predominate in the marrow, lymph nodes, and spleen
- Decreased LAP, philadelphia chromosome (bcr/abl)
Clot busters - correct answer--streptokinase
-tpa=tissue plasminogen activator that convert inactive plasminogen into plasmin
-Urokinase
Clot Retraction - correct answer-1. Evaluates platelet function, fibrinogen, red cell volume
and fibrinolytic activity
2. Abnormal if platelet count < 100 x 10^9 /L
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Hkane. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £6.57. You're not tied to anything after your purchase.
