ASCP Hematology Exam-MLT
D. Golgi area - ✅✅-The light-colored zone adjacent to the nucleus in a
plasmacyte is the:
A. ribosome
B. chromatin
C. mitochondria
D. Golgi area
A. hemoglobin - ✅✅-The majority of the iron in an adult is found as a
constituent of:
A. hemoglobin
B. hemosiderin
C. myoglobin
D. transferrin
B. provide the level 2,3-DPG - ✅✅
-The main function of the hexose
monophosphate shunt in the erythrocyte is to:
A. reglate the level of 2,3-DPG
B. provide reduced glutathione to prevent oxidation of hemoglobin
C. prevent the reduction of heme iron
D. provide energy for membrane maintenance
D. in the ferrous state - ✅✅-In order for hemoglobin to combine reversibly with
oxygen, the iron must be:
A. complexed with haptoglobin
B. freely circulating in the cytoplasm
C. attached to transferrin
D. in the ferrous state
D. myeloid metaplasia - ✅✅ -In which of the following disease states are
teardrop cells and adnormal platelets most characteristically seen?
,A. hemolytic anemia
B. multiple myeloma
C. G-6-PD deficiency
D. myeloid metaplasma
D. removal of imperfect and aging cells - ✅✅-In the normal adult, the spleen
acts as a site for:
A. storage of red blood cells
B. production of red blood cells
C. synthesis of erythropoietin
D. removal of imperfect and aging cells
B. iron, protoporphyrin, and globin - ✅✅ -After removal of red blood cells from
the circulation hemoglobin is broken down into:
A. iron, porphyrin, and amino acids
B. iron, protoporphyrin, and globin
C. heme, protoporphyrin, and amino acids
D. heme, hemoseridin, and globin
✅✅
D. denatured hemoglobin inclusions that are readily removed by the spleen -
-Heinz bodies are:
A. readily identified with polychrome stains
B. rarely found in glucose-6-phosphate dehydrogenase deficient erythrocytes
C. closely associated with spherocytes
D. denatured hemoglobin inclusions that are readily removed by the spleen
A. erythrocytes - ✅✅-Cells for the transport of O2 and CO2 are:
A. erythrocytes
B. granulocytes
C. lymphocytes
D. thrombocytes
B. stimulate RNA synthesis of erythroid cells - ✅✅-Erythropoeitin acts to:
, A. shorten the replication time of the granulocytes
B. stimulate RNA synthesis of erythroid cells
C. increase colony-stimulating factors produced by the B-lymphocytes
D. decrease the release of marrow reticulocytes
C. spherocytes - ✅✅-What cell shape is most commonly associated with an
increase MCHC?
A. teardrop cells
B. target cells
C. spherocytes
D. sickle cells
B. red cell membrane defects - ✅✅
-Which of the following characteristics are
common to hereditary spherocytosis, hereditary elliptocytosis, hereditary
stomatocytosis, and paroxysmal nocturnal hemoglobinuria?
A. autosomal dominant inheritance
B. red cell membrane defects
C. positive direct anti-globulin test
D. measured platelet count
D. chronic blood loss - ✅✅ -Which of the following is most closely associated
with iron deficiency anemia?
A. iron overload in tissue
B. target cells
C. basophilic stippling
D. chronic blood loss
✅✅
B. a quantitative deficiency in RNA resulting in decreased globin chain production
- -Evidence indicates that the generic defect in thalassemia usually results
in?
A. the production of abnormal globin class
B. a quantitative deficiency in RNA resulting in decreased globin chain production
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