100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Previously searched by you
Previously searched by you
logo
ILE 8- OA PAIN Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution £6.46   Add to cart
Quickly navigate to
Preview
  2.  
  3. All Summer Modules Studies 2024
  4.  
  5. All Summer Modules Studies 2024
  6.  
  7. All summer modules studies 2024

Exam (elaborations)

ILE 8- OA PAIN Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution

1 review
 8 views  0 purchase

ILE 8- OA PAIN Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution

Preview 2 out of 9  pages

Document information

  • June 19, 2024
  • 9
  • 2023/2024
  • Exam (elaborations)
  • Questions & answers

Subjects

  • ile 8 oa pain questions with 100 actual correct

Written for

All documents for this subject (274)

1  review

review-writer-avatar

By: EXAMQA • 4 months ago

Seller

avatar-seller
Hkane

Reviews received

Content preview

ILE 8- OA/PAIN
Steps of Pain progression
Transduction
Conduction
Transmission
Perception
Modulation
Osteoarthritis is due to
Wear and tear on the joints
OA usually occurs in
hips, knees, hands
pathophys of OA
Peri-artic ular muscle weakness
Cartilage destruction
bone remodeling
Cartilage destruction mediated by
TNF, IL, receptors and transcription factors
bone modulators such as __ regulate remodeling
biphsophonate
etiology of OA
Obesity
Trauma
Genetics
Reduces levels of sex hormones
Muscle weakness
Reptitive use
Jobs requiring heavy labor
Infection
clinical presentation OA: age
Usually older
clinical presentation OA: gender
Age < 45 more common in men
Over 45 more common in women
symptoms OA
-Pain
-Deep aching
-Pain on motion
-Stiffness in affected joints
pain in OA usually resolved with
motion, recurs with rest
Gelling
Usually duration < 30 min
pain in OA can be

, weather-related
non-pharm OA
Exercise
Weight loss
Patient education
Assistive device
Shoe insoles
Heat
NSAIDS inhibit action of
cyclooxygenase
cyclooxygenase is responsible for converting
arachidonic acid to prostaglandins
Two types of cyclooxygenase
COX 1 and 2
Throughout body
Cell signaling and tissue maintenance
Undesirable side effects when inhibited
COX 1
Expressed in inflammatory cells
Makes prostaglandins
COX 2
COX 2 has 3 domains
Binding site for EGF
Membrane binding
Catalytic domain
Major actions of prostaglandins
PGD2
Weak inhibitor of platelet aggregation
Major actions of prostaglandins
PGE1
-Vasodilation
-Inhibitor of lipolysis
-Inhibitor of platelet aggregation
-Bronchodilation
-Contraction of smooth GI
Major actions of prostaglandins
PGE2
-Stimulates hyperalgesic response
-Renal vasodilation
-Stimulates uterine smoothe muscle contraction
-Protect GI
-Reduce secretion of stomach acid
Major actions of prostaglandins
PGF2

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller Hkane. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for £6.46. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

81113 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy revision notes and other study material for 14 years now

Start selling
£6.46
  • (1)
  Add to cart