Beta 1 receptors are found primarily in the _________ and stimulation of them causes an
__________ in heartbeat - correct answer-heart; increase
Beta blockers cause an increase/decrease in heart rate - correct answer-decrease
Cardiac glycosides (digoxin) have a low/high therapeutic index - correct answer-low
Clozapine (Clozaril) has what potentially fatal side effect? - correct answer-agranulocytosis
Define agonist - correct answer-a compound that binds to a receptor and produces the
biological response
Define antagonists - correct answer-- block or reverse the effect of agonists
- have no effect on their own
Define Drug receptor - correct answer-a specialized target macromolecule that binds a drug
and mediates its pharmacological action
Define first pass effect - correct answer-the phenomenon of drug metabolism whereby the
concentration of a drug is greatly reduced before it reaches the systemic circulation
Define hemostasis - correct answer-process which causes bleeding to stop
Define tardive dyskinesia and what class of drugs can bring on this side effect? - correct
answer-- muscle twitches, especially around the mouth and tongue
- involuntary sucking, shewing, lip smacking
- sometimes in the whole body
- first generation antipsychotics
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