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portage pharm exam 1 studyguide.
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- Gpstc Criminal Law.
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- Gpstc Criminal Law.
portage pharm exam 1 studyguide.
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portage pharm exam 1 studyguideShow how you would set up a proportion for a basic drug calculation. - correct
answer-10mg/kg = Xmg/50mg where you solve for "X"
How many pounds are in 1 Kg? - correct answer-2.2 lbs
Adverse effects - correct answer-undesired effects that is potentially harmful
define the terms Drug tolerance and Drug dependence. - correct answer-Drug tolerance is
defined as a decreased effect that occurs after repeated administration.
Drug dependence is a condition wherein reliance on the administration of a particular drug
becomes extremely important to the well-being of the individual. This can be psychological
and physical.
side effects - correct answer-drug effects other than the therapeutic effect that are
undesirable but not harmful.
List the pregnancy drug classes and name the one that is considered most safe for use in
pregnancy. - correct answer-Pregnancy Category A, B, C, D, X, NR. Pregnancy category A
is considered most safe.
Define receptors and the two different ways in which they can act. - correct
answer-Receptors are specific cellular structures that bind to drugs, when bind they produce
a physiologic effect *antagonist which interfere with the drugs effects *Agonist witch activate
the drug effects
Where is the most common site of drug interactions? - correct answer-The most common
drug interactions happen when there is competition between two drugs for metabolizing
enzymes within the cytochrome P-450 enzymes
What is the difference between the onset of action and duration of action? - correct
answer-Onset is the time between drug given to when the effects is seen
Duration is the length of time the drug shows its effect
List factors that affect how a person responds to drug therapy. - correct answer-Age
\Absorption- Drug absorption is delayed due to decreased intestinal blood flow, surface area
and motility- this slows the onset of actionDistribution-distribution is increased leading to
increased drug effect due to decreased body water, lean body mass and increased fat
contentMetabolism - Drug metabolism decreases increasing the duration of the drug due to
decrease in blood flow to the liver and decrease in liver enzymesExcretion - Excretion is
decreased due to decreased blood flow to the kidneys and overall decreased renal function
as one ages
weight -Most adult dosages are calculated for a 150-pound adult. If a person is significantly
larger or smaller their dose may need to be adjusted.Higher body fat percentage means that
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