Exam (elaborations)
PHAR 1.
- Module
- Gpstc Criminal Law.
- Institution
- Gpstc Criminal Law.
Exam of 13 pages for the course gpstc Criminal Law. at gpstc Criminal Law. (PHAR 1.)
[Show more]
Seller
Follow
Content preview
PHAR 1What is Pharmacology?
· study of how chemical agents (drugs) can influence the function of living systems
What does Pharmacodynamics cover?
'what the drug does to the body'
What is Pharmacokinetics?
'what the body does to the drug'
Where is the euphoric 'high' effect of cocaine produced?
dopaminergic neurons in the nucleus accumbens
What are the 4 types of drug target proteins?
• receptors
• enzymes
• ion channels
• carrier proteins
What is the drug target interaction of aspirin?
Binds to 'enzyme' cyclooxygenase and blocks the production of prostaglandins
What is the drug target interaction of local anaesthetic?
• blocks sodium 'ion channels'
, • prevents nerve conduction
What is the drug target interaction of prozac (anti-depressant)?
• blocks serotonin 'carrier proteins'
• prevents serotonin being removed from the synapse
What is the drug target interaction of nicotine?
Binds to and activates the nicotinic acetylcholine 'receptor'
How can drugs act on targets?
• enhance activation of the target (stimulate an effect)
• or prevent activation of the target (block an effect from being produced)
What is required for a drug to be an effective therapeutic agent?
· must show a high degree of specificity for a particular drug target
Why is it difficult to design a drug that only binds to one target?
Many drugs are and chemicals are structurally similar
· E.g. 3 endogenously produced chemicals: dopamine, noradrenaline and serotonin
What is the structure of dopamine?
• contains a catechol structure (benzene ring with 2 hydroxyl side groups)
- with one amine group attached via an ethyl side chain
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller modockochieng06. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £6.29. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
80435 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy revision notes and other study material for 14 years now