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Exam (elaborations)

M02-FL03 Vasodilators

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M02-FL03 Vasodilators

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  • June 24, 2024
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  • 2023/2024
  • Exam (elaborations)
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M02-FL03 Vasodilators

A cardiac reflex in response to hypotension - ANS-Tachycardia, stimulation of RAA

A drug used to prolong the action of lidocaine - ANS-epinephrine

A high dose of nitroglycerin does this - ANS-Decreases pre-load and afterload

A loading dose acheives steady-state: True or False - ANS-FALSE

ACE inhibitor effects in the kidneys will not result in renal decompensation as long as
this occurs - ANS-Cardiac output increases (in the healthy heart) as a result of
decreased afterload

ACE inibitors are associated with reno protection in pateints with progressive renal
disease (T or F) - ANS-TRUE

Afterload vessels - ANS-precapillary arterioles

Amlodipine acts as a negative inotrope (T or F) - ANS-FALSE

Amlodipine may inhibit drug metabolizing enzymes (T or F) - ANS-FALSE

An approach to limit the effect of nitroglycerin to preload reduction - ANS-Low dose

An indicator of acute renal decompensation following ACE inhibitor therapy -
ANS-Increased serum creatinine

Capacitance vessels - ANS-venules

Capacitance: venous or arterial? - ANS-Venous

Common adversity of afterload reducer - ANS-Hypotension

Drugs which increase the risk of renal decompensation following ACE inhibitor therapy -
ANS-NSAIDs, aminoglycosides, diuretics

, Enalapril is not absorbed in this species - ANS-Horse

Half-life of amlodipine in dogs - ANS-30 hrs

Hypertension is a common malady of dogs (T or F) - ANS-FALSE

If designing a loading dose, and the target concentration is known, the dose is
calculated based on: - ANS-Volume of distribution and oral bioavailability

Impact of inhibiting cAMP in smooth muscle - ANS-contraction

Impact of stimulating cAMP in smooth muscle - ANS-relaxation

Mechanism by which acepromazine causes vasodilation - ANS-dc

Mediators causing vasoconstriction of arterioles - ANS-Angiotensin II, vasopressin,
endothelin, epi and norepi

Nitrates are convertid to nitric oxide in the vascular endothelial cell (T or F) - ANS-TRUE

Nitroglycerin is orally bioavailable (T or F) - ANS-FALSE

Nitroprusside is used for emergency treatment of this - ANS-Increased afterload,
inlcuding hypertension

Other than half-live, a reason for delayed response to amlodipine - ANS-Binding and
saturating receptors

Preload vessels - ANS-Venules

Resistance vessels - ANS-precapillary arterioles

Resistance: venous or arterial? - ANS-Arterial

Risk factors for renal decompensation following ACE inhibitor therapy - ANS-Renal
disease, severe myocardial disease, hyponatremia

Standard routes of nitroglycerin therapy in animals - ANS-Transdermal

The active form of enalapril - ANS-Enaliprat

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