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Exam (elaborations)

USMLE Step 1 Pharm

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Exam of 28 pages for the course CTR exam quizzes with A+Answers 2024 at CTR exam quizzes with A+Answers 2024 (USMLE Step 1 Pharm)

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  • June 24, 2024
  • 28
  • 2023/2024
  • Exam (elaborations)
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denicetho
USMLE Step 1 Pharm
-dronate - ANS-Bisphosphonate drug. Bone resorption inhibitor. Osteoporosis, Paget's,
Hypercalcemia

Acarbose - ANS-Alpha-glucosidase inhibitor. Blocks saccharide degradation and thus
glucose absorption by gut. Causes bloating.

Miglitol - ANS-Alpha-glucosidase inhibitor. Blocks saccharide degradation and thus
glucose absorption by gut. Causes bloating.

Mifepristone - ANS-Progesterone antagonist, Abortion, keep mi vagina pristine

Danazol - ANS-Androgen that blocks FSH, LH. Endometriosis.

Ergocalciferol - ANS-Vitamin D

Finasteride - ANS-5 alpha reductase inhibitor. Blocks DHT formation, baldness, BPH.

Fludrocortisone - ANS-Mineralocorticoid agonist. Adrenal insufficiency.

Glipizide - ANS-Sulfonylurea. Block ATP K channels to promote insulin release. Helps
insulin glide out of beta cells

Glimepiride - ANS-Sulfonylurea. Block ATP K channels to promote insulin release.
Helps insulin glide out of beta cells

Glyburide - ANS-Sulfonylurea. Block ATP K channels to promote insulin release. Helps
insulin glide out of beta cells

Aspart - ANS-Short-term insulin

Glulisine - ANS-Short-term insulin

Lispro - ANS-Short-term insulin

Insulin NPH - ANS-Medium length insulin.
Glargine - ANS-Long term insulin. Quite glarging around glucose, this insulin is

,determined!

Determir - ANS-Long term insulin. Quite glarging around glucose, this insulin is
determined!

Metformin - ANS-Decrease hepatic glucose output. Prevents formation of glucose

Methimazole - ANS-Thyroid hormone synthesis inhibitor.

Octreotide - ANS-Blocks GH, IGF-1, Serotonin, Gastroactive peptides Oxytocin -

ANS-Contracts uterus. Induce labor, stop uterine bleeding. Promote lactation.

Pegvisomant - ANS-GH antagonist. Acromegaly. Peg down your height!

Pioglitazone - ANS-Sensitizes muscle and adipose to insulin. Gets muscle and adipose
in the "zone" to accept insulin.

Risoglitazone - ANS-Sensitizes muscle and adipose to insulin. Gets muscle and
adipose in the "zone" to accept insulin.

Pramlintide - ANS-Amylin analog. Slows gastric emptying and makes you feel full. Less
glycemia after meals. Pram down all the food you want, your body wont absorb the
glucose.

Raloxifene - ANS-Bone resorption inhibitor. Estrogen agonist selective for bone. Relax
bone, you don't need to degrade, raloxifene is here.

Repaglinide - ANS-Stimulates insulin release. Also has the glide like sulfonylurea. Helps
insulin glide out of beta cells.

Nateglinide - ANS-Stimulates insulin release. Also has the glide like sulfonylurea. Helps
insulin glide out of beta cells.

Sitagliptin - ANS-DPP4 inhibitor, enhances incretin (GLP-1) action, which enhances
insulin secretion, muscle/fat uptake, decreases glucagon secretion.

Teriparatide - ANS-PTH, postmenopausal women. May cause osteosarcoma
-thromycin - ANS-Macrolide. 50S inhibitor.

, Aztreonam - ANS-Monobactam. Pseudomonas and enterobacteriae

Caspofungin - ANS-Antifungal that inhibits fungal cell wall synthesis

Cephalexin - ANS-1st gen cephalosporin

Ceftriaxone - ANS-3rd gen cephalosporin: pneumonia, gonorrhea, otitis media

Cefepime - ANS-4th gen cephalosporin. Citrobacter, enterobacter -floxacin -

ANS-Fluoroquinolones,topo2 inhibitor, tendionopathy/arthropathy Clindamycin

- ANS-50s inhibitor. Causes enterocolitis

Doxycycline - ANS-30S inhibitor. Teeth discoloration, photosensitivity. Intracellular bugs

Tetracycline - ANS-30S inhibitor. Teeth discoloration, photosensitivity. Intracellular bugs

Acyclovir - ANS-DNA polymerase inhibitor. Herpes zoster or simplex. Amphotericin B -

ANS-Binds ergosterol and forms K channel. Nephrotoxic. Clavulanate -

ANS-B-lactamase inhibitors

Tazobactam - ANS-B-lactamase inhibitors

Albendazole - ANS-Tubulin inhibitor, starves worms. Intestinal nematode infections.

Ethambutol - ANS-Mycobacteria drug that inhibits RNA synthesis. Can cause optic
neuritis. Causes things to appear Ethereal!

Foscarnet - ANS-Blocks viral DNA polymerase. CMV, resistant herpes. Renal failure

Fosfomycin - ANS-UTI's.

Gancyclovir - ANS-Blocks viral DNA polymerase. CMV. Decreases visual acuity, bone
marrow suppression

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