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Lecture notes

Organelles (Biomedical Science)

This document provides an in-depth overview of the various organelles found in eukaryotic cells, highlighting their structure, functions, and unique characteristics.

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  • June 24, 2024
  • June 24, 2024
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  • Dr zita balklava
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Cells To Systems - Organelles
Organelles

Eukaryotic Are Divided Into Compartments:

 Organelles - Cell is divided into different components
 Discrete structures of a eukaryotic cell
 Each organelle carries out specialised functions
 Has an enclosed membrane (mostly)
 Distributed throughout the cytoplasm on the cells

Nucleus:

 Most prominent organelle in the cell
Nucleus
 Big (3 - 10 µm)
 Contains characteristics of eukaryotic Nucleolus
 Contains the genome within nucleoplasm
 Has chromosomes and proteins
 Site of DNA storage
 Site of DNA and RNA synthesis
 Inside the nucleus is the nucleolus and cytoplasm

Chromosomes:

 Not always visible
 Undergo mitosis and start to condense
 They become visible as a cell is about to divide

Nucleolus:
Sub-nuclear Structure - Consists of either
 Is a sub-nuclear structure
proteins; proteins & RNA; proteins & DNA;
 Site of ribosome production They will come together, combine and proteins, DNA & RNA
 rRNA will be synthesised be exported out of the nucleus
 It is not membrane bound rRNA - Ribosome RNA
 The sizes vary depending on the number of ribosomes produced (more ribosomes = bigger)

Nuclear Envelope:

 It is a double lipid bilayer with pores where inner and outer membranes connect
 The envelope is penetrated by pores (which are symmetrical)
 The pores act as gates to allow RNA, proteins and other molecules to move
appropriately
 Provides Quality Control - Proteins will determine what will go inside and
outside e.g. only mature mRNA (messenger RNA) leaves the nucleus

Nuclear Support:

 Supported mechanically by networks of intermediate filaments e.g. cytoskeleton both on the outside
and inside the nuclear envelope e.g. nuclear lamina (located inside)
 Has a fibrous network




Endoplasmic Reticulum:

1

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