Anemia - ANSWER-Decrease in total number of erythrocytes in circulation blood
or quality or quantity of hemoglobin
Classifications of anemia - ANSWER-microcytic, normocytic, macrocytic
microcytic hypochromic anemia - ANSWER-Disorders of hemoglobin synthesis,
iron deficiency
, macrocytic anemia - ANSWER-Abnormal maturation of erythrocyte precursors on
bone marrow, usually due to deficiency in B12 and/or folate which affects DNA
synthesis
normocytic normochromic anemia - ANSWER-Characterized by red cells that are
relatively normal in size and hemoglobin content but insufficient in number, shape
of RBC helps determine cause/type
anisocytosis - ANSWER-presence of red blood cells of various sizes
poikilocytosis - ANSWER-condition characterized by red blood cells in a variety
of shapes
Eryptosis - ANSWER-premature death of damaged erythrocytes
intrinsic factor - ANSWER-Protein transporter necessary for absorption of vitamin
B12
pernicious anemia (PA) - ANSWER-Chronic, progressive anemia found mostly in
people older than age 50 resulting from a lack of sufficient vitamin B12 needed
for blood cell development. Usually related to lack of intrinsic factor from gastric
parietal cells required for absorption.
Erythropoiesis - ANSWER-production of red blood cells
Hematopoiesis - ANSWER-blood cell formation in bone marrow
Hemostasis - ANSWER-to stop or control bleeding
Mechanism of hemostasis - ANSWER-1. Blood vessel wall injured, collagen
fibers exposed at damaged site
2. Release of *endothelin* (vasoconstrictor) & von Willebrand (vWF) which bonds
exposed collagen fibers
3. Platelets adhere to exposed collagen *by binding to vWF* and they get
activated (*platelet activation*)
- platelet shape transformation
- platelet degranulation (a/d granules)
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller stephanvdb04. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £10.95. You're not tied to anything after your purchase.
