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Class notes TOEFL Robbins Patologia Humana
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  • Robbins Patologia Humana

Lecture notes study book Robbins Patologia Humana of Vinay Kumar, Abul K. Abbas, Stanley L. Robbins, Nelson Fausto, Richard N. Mitchell (Hypertensive vascular disease) - ISBN: 9788480863322 (Short and pricise)

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Document information

  • July 15, 2024
  • 51
  • 2023/2024
  • Lecture notes
  • Dr birtukan ,phatologist
  • Pc1

Subjects

  • robbins
  • phatology
  • 10th

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Content preview

Hypertensive
Vascular Disease &
Aneurysm
Dr Birtukan Ewunetu (MD, Pathologist)



07/15/2024

, Outlines
Blood pressure regulation
Hypertension and its complications
Vascular wall response to injury
Types of Hypertensive heart disease
Aneurysm and aortic dissection




07/15/2024

, Blood pressure regulation
Blood pressure is determined by cardiac out put and
vascular resistance
Vascular resistance is regulated at the level of the
arterioles, influenced by neural (adrenergic) and
hormonal (angiotensin) inputs
Cardiac output is determined by heart rate and stroke
volume
Blood volume in turn is regulated mainly by renal
sodium excretion or resorption


07/15/2024

, Cont’d
Kidneys influence peripheral resistance and
sodium excretion/retention primarily through the
renin angiotensin system

Renin, a major regulator of blood pressure, is
secreted by the kidneys in response to decreased
blood pressure

Renin cleaves angiotensinogen to angiotensin I
Angiotensin I converted to angiotensin II by ACE

07/15/2024

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